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Number of items: 101.

Vasu, S, McClenaghan, Neville, McCluskey, Janie and Flatt, Peter (2013) Cellular responses of novel human pancreatic β-cell line, 1.1B4 to hyperglycemia. Islets, 5 (4). 0-0. [Journal article]

Vasu, S, McClenaghan, Neville, McCluskey, Janie and Flatt, Peter (2013) Effects of lipotoxicity on novel insulin secreting human pancreatic β-cell line, 1.1B4. Biological Chemistry, 394 (7). pp. 909-918. [Journal article]

Vasu, Srividya, McClenaghan, Neville, McCluskey, Janie and Flatt, Peter (2013) Mechanisms of toxicity by proinflammatory cytokines in a novel human pancreatic beta cell line, 1.1B4. Biochimica et Biophysica Acta , 1840 (1). pp. 136-145. [Journal article]

Abed, Arif, Critchlow, Charlotte, Flatt, Peter, McClenaghan, Neville and Kelly, Catriona (2012) Directed differentiation of progenitor cells towards an islet-cell phenotype. Am J Stem Cells., 1(3) . pp. 196-204. [Journal article]

da Silva Krause , M, Bittencourt , A, Homem de Bittencourt , PI jr, McClenaghan, Neville, Flatt, Peter, Murphy , C and Newsholme , P (2012) Physiological concentrations of interleukin-6 directly promote insulin secretion, signal transduction, nitric oxide release, and redox status in a clonal pancreatic β-cell line and mouse islets. Journal of Endocrinology, 214 (3). pp. 301-311. [Journal article]

Guo-Parke, H, McCluskey, Janie, Kelly , C, Hamid , M, McClenaghan, Neville and Flatt, Peter (2012) Configuration of electrofusion-derived human insulin-secreting cell line as pseudoislets enhances functionality and therapeutic utility. Journal of Endocrinology , 214 (3). pp. 257-265. [Journal article]

Guo-Parke, H., McCluskey, Janie, Kelly, Catriona, Hamid, M., McClenaghan, Neville and Flatt, Peter (2012) Configuration of electrofusion-derived human insulin-secreting cell line as pseudoislets enhances functionality and therapeutic utility. Journal of Endocrinology, 214 (3). p. 257. [Journal article]

McClenaghan, Neville, Flatt, Peter, Harper, AGS and Kelly, Catriona (2012) Establishment of an F508del pseudoislet model for the study of CF-related diabetes. Journal of Cystic Fibrosis, 11 . S117. [Journal article]

Scullion, S. M. J., Gurgul-Convey, E., Elsner, M., Lenzen, S., Flatt, Peter and McClenaghan, Neville (2012) Enhancement of homocysteine toxicity to insulin-secreting BRIN-BD11 cells in combination with alloxan. JOURNAL OF ENDOCRINOLOGY, 214 (2). pp. 233-238. [Journal article]

Irwin, Nigel, McKinney, J. M., Bailey, C. J., McClenaghan, Neville and Flatt, Peter (2011) Acute and Long-term Effects of Peroxisome Proliferator-activated Receptor-gamma Activation on the Function and Insulin Secretory Responsiveness of Clonal Beta-Cells. HORMONE AND METABOLIC RESEARCH, 43 (4). pp. 244-249. [Journal article]

Kelly, Catriona, Flatt, Cara C. S. and McClenaghan, Neville (2011) Stem Cell-Based Approaches for the Treatment of Diabetes. Stem Cells International, 2011 . p. 1. [Journal article]

Kelly, Catriona, McClenaghan, Neville and Flatt, Peter (2011) Role of islet structure and cellular interactions in the control of insulin secretion. Islets. , 3(2) . pp. 41-47. [Journal article]

Kelly, Catriona, McClenaghan, Neville H. and Flatt, Peter (2011) Role of islet structure and cellular interactions in the control of insulin secretion. ISLETS, 3 (2). pp. 41-47. [Journal article]

Krause, MS, McClenaghan, Neville, Flatt, Peter, de Bittencourt, PIH, Murphy, C and Newsholme, P (2011) L-Arginine is essential for pancreatic beta-cell functional integrity, metabolism and defense from inflammatory challenge. JOURNAL OF ENDOCRINOLOGY, 211 (1). pp. 87-97. [Journal article]

McCluskey, Janie, Hamid, Muhajir, Guo-Parke, Hong, McClenaghan, Neville, Gomis, Ramon and Flatt, Peter (2011) Development and Functional Characterization of Insulin-releasing Human Pancreatic Beta Cell Lines Produced by Electrofusion. JOURNAL OF BIOLOGICAL CHEMISTRY, 286 (25). pp. 21982-21992. [Journal article]

Irwin, Nigel, McKinney, J. M., Bailey, C. J., Flatt, Peter and McClenaghan, Neville (2010) Effects of metformin on BRIN-BD11 beta-cell insulin secretory desensitization induced by prolonged exposure to sulphonylureas. DIABETES OBESITY & METABOLISM, 12 (12). pp. 1066-1071. [Journal article]

Kelly, C., Parke, H. Guo, McCluskey, Janie, Flatt, Peter and McClenaghan, Neville (2010) Evaluation of role of islet cell paracrine interactions in regulation of insulin secretion using a new heterotypic pseudoislet model. REGULATORY PEPTIDES, 164 (1, Sp. Iss. SI). p. 33. [Journal article]

Kelly, Catriona, Flatt, Peter and McClenaghan, Neville (2010) Cell-to-cell communication and cellular environment alter the somatostatin status of delta cells. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 399 (2). pp. 162-166. [Journal article]

Kelly, Catriona, Flatt, Peter and McClenaghan, Neville (2010) Cell-to-cell communication and cellular environment alter the somatostatin status of delta cells. Biochemical and Biophysical Research Communications, 399 (2). p. 162. [Journal article]

Kelly, Catriona, Guo, Hong, McCluskey, Janie, Flatt, Peter and McClenaghan, Neville (2010) Comparison of Insulin Release From MIN6 Pseudoislets and Pancreatic Islets of Langerhans Reveals Importance of Homotypic Cell Interactions. PANCREAS, 39 (7). pp. 1016-1023. [Journal article]

Kelly, Catriona, Guo, Hong, McCluskey, Janie, Flatt, Peter and McClenaghan, Neville (2010) Comparison of Insulin Release From MIN6 Pseudoislets and Pancreatic Islets of Langerhans Reveals Importance of Homotypic Cell Interactions. Pancreas, 39 (7). p. 1016. [Journal article]

Kelly, Catriona, Parke, Hong Guo, McCluskey, Janie, Flatt, Peter and McClenaghan, Neville (2010) The role of glucagon- and somatostatin-secreting cells in the regulation of insulin release and beta-cell function in heterotypic pseudoislets. DIABETES-METABOLISM RESEARCH AND REVIEWS, 26 (7). pp. 525-533. [Journal article]

Kelly, Catriona, Parke, Hong Guo, McCluskey, Janie, Flatt, Peter and McClenaghan, Neville (2010) The role of glucagon- and somatostatin-secreting cells in the regulation of insulin release and beta-cell function in heterotypic pseudoislets. Diabetes/Metabolism Research and Reviews, 26 (7). p. 525. [Journal article]

McKiney, Joan M., Irwin, Nigel, Flatt, Peter, Bailey, Clifford J. and McClenaghan, Neville (2010) Acute and long-term effects of metformin on the function and insulin secretory responsiveness of clonal beta-cells. BIOLOGICAL CHEMISTRY, 391 (12). pp. 1451-1459. [Journal article]

Persaud , SJ, Arden, C, Bergsten, P, Bone , AJ, Brown, J, Dunmore, S, Harrison, M, Hauge-Evans, A, Kelly, Catriona, King , A, Maffucci , T, Marriott , CE, McClenaghan, Neville, Morgan, N, Reers, C, Russell, MA, Turner, MD, Willoughby, E, Younis , MY, Zhi, ZL and Jones, PM (2010) Pseudoislets as primary islet replacements for research: report on a symposium at King's College London, London UK. Islets. 2010 Jul-Aug;2(4):236-9., 2(4) . pp. 236-239. [Journal article]

Bender, Katrin, Maechler, Pierre, McClenaghan, Neville H., Flatt, Peter and Newsholme, Philip (2009) Overexpression of the malate-aspartate NADH shuttle member Aralar 1 in the clonal beta-cell line BRIN-BD11 enhances amino-acid-stimulated insulin secretion and cell metabolism. CLINICAL SCIENCE, 117 (9-10). pp. 321-330. [Journal article]

Kiely A, A, Robinson A, A, McClenaghan, Neville H., Flatt, Peter and Newsholme P, P (2009) Toll-like receptor agonist induced changes in clonal rat BRIN-BD11 beta-cell insulin secretion and signal transduction. Journal of Endocrinology, 202 (3). pp. 365-373. [Journal article]

McClenaghan, Neville, Scullion, Siobhan M., Mion, Brian, Hewage, Chandralal, Malthouse, J. Paul G., Flatt, Peter, Newsholme, Philip and Brennan, Lorraine (2009) Prolonged L-alanine exposure induces changes in metabolism, Ca2+ handling and desensitization of insulin secretion in clonal pancreatic beta-cells. CLINICAL SCIENCE, 116 (3-4). pp. 341-351. [Journal article]

Liu, Hui-Kang, McCluskey, Janie, McClenaghan, Neville and Flatt, Peter (2008) Iterative exposure of clonal BRIN-BD11 cells to ninhydrin enables selection of robust toxin-resistant cells but with decreased gene expression of insulin secretory function. PANCREAS, 36 (3). pp. 294-301. [Journal article]

Brennan, L., Scullion, S. M., Mion, B., Hewage, C., Malthouse, J. P. G., Flatt, Peter, Newsholme, P. and McClenaghan, Neville H. (2007) Prolonged alanine exposure induces changes in metabolism, Ca2+ handling and desensitization of insulin secretion in clonal pancreatic beta cells. DIABETOLOGIA, 50 (Suppl. 1). 0509. [Journal article]

Kiely, Aoife, McClenaghan, Neville, Flatt, Peter and Newsholme, Philip (2007) Pro-inflammatory cytokines increase glucose, alanine and triacylglycerol utilization but inhibit insulin secretion in a clonal pancreatic beta-cell line. JOURNAL OF ENDOCRINOLOGY, 195 (1). pp. 113-123. [Journal article]

Liu, Hui-Kang, McCluskey, Janie, McClenaghan, Neville and Flatt, Peter (2007) Streptozotocin-resistant BRIN-BD11 cells possess wide spectrum of toxin tolerance and enhanced insulin-secretory capacity. ENDOCRINE, 32 (1). pp. 20-29. [Journal article]

Patterson, Steven, Flatt, Peter and McClenaghan, Neville (2007) Homocysteine-induced impairment of insulin secretion from clonal pancreatic BRIN-BD11 beta-cells is not prevented by catalase. PANCREAS, 34 (1). pp. 144-151. [Journal article]

Patterson, Steven, Flatt, Peter and McClenaghan, Neville (2007) Major metabolic homocysteine-derivative, homocysteine thiolactone, exerts changes in pancreatic beta-cell glucose-sensing, cellular signal transduction and integrity. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 461 (2). pp. 287-293. [Journal article]

Patterson, Steven, Scullion, Siobhan M. J., McCluskey, Janie, Flatt, Peter and McClenaghan, Neville (2007) Prolonged exposure to homocysteine results in diminished but reversible pancreatic beta-cell responsiveness to insulinotropic agents. DIABETES-METABOLISM RESEARCH AND REVIEWS, 23 (4). pp. 324-334. [Journal article]

Brennan, Lorraine, Hewage, Chandralal, Malthouse, J. P. G., McClenaghan, Neville, Flatt, Peter and Newsholme, Philip (2006) Investigation of the effects of sulfonylurea exposure on pancreatic beta cell metabolism. FEBS JOURNAL, 273 (22). pp. 5160-5168. [Journal article]

Corless, Mary, Kiely, Aoife, McClenaghan, Neville, Flatt, Peter and Newsholme, Philip (2006) Glutamine regulates expression of key transcription factor, signal transduction, metabolic gene, and protein expression in a clonal pancreatic beta-cell line. JOURNAL OF ENDOCRINOLOGY, 190 (3). pp. 719-727. [Journal article]

Liu, Hui-Kang, Green, Brian D., McClenaghan, Neville, McCluskey, Janie and Flatt, Peter (2006) Deleterious effects of supplementation with dehydroepiandrosterone sulphate or dexamethasone on rat insulin-secreting cells under in vitro culture condition. BIOSCIENCE REPORTS, 26 (1). pp. 31-38. [Journal article]

Marenah, Lamin, McCluskey, Janie, Abdel-Wahab, Yasser, O'Harte, Finbarr, McClenaghan, Neville and Flatt, Peter (2006) A stable analogue of glucose-dependent insulinotropic polypeptide, GIP(LysPAL(16)), enhances functional differentiation of mouse embryonic stem cells into cells expressing islet-specific genes and hormones. BIOLOGICAL CHEMISTRY, 387 (7). pp. 941-947. [Journal article]

McClenaghan, Neville, Flatt, Peter and Ball, Andrew J. (2006) Actions of glucagon-like peptide-1 on K-ATP channel-dependent and -independent effects of glucose, sulphonylureas and nateglinide. JOURNAL OF ENDOCRINOLOGY, 190 (3). pp. 889-896. [Journal article]

Patterson, Steven, Flatt, Peter, Brennan, L., Newsholme, P. and McClenaghan, Neville (2006) Detrimental actions of metabolic syndrome risk factor, homocysteine, on pancreatic beta-cell glucose metabolism and insulin secretion. JOURNAL OF ENDOCRINOLOGY, 189 (2). pp. 301-310. [Journal article]

Patterson, Steven, Flatt, Peter and McClenaghan, Neville (2006) Homocysteine and other structurally-diverse amino thiols can alter pancreatic beta cell function without evoking cellular damage. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1760 (7). pp. 1109-1114. [Journal article]

Ball, AJ, Flatt, Peter and McClenaghan, Neville (2005) Alterations of insulin secretion following long-term manipulation of ATP-sensitive potassium channels by diazoxide and nateglinide. BIOCHEMICAL PHARMACOLOGY, 69 (1). pp. 59-63. [Journal article]

Brennan, L, Hewage, C, Malthouse, JG, McClenaghan, Neville, Flatt, Peter and Newsholme, P (2005) Effects of anti-diabetic drugs on beta cell glucose metabolism in a clonal cell line, BRIN-BD11. DIABETOLOGIA, 48 (Suppl. 1). p. 439. [Journal article]

Cunningham, GA, McClenaghan, Neville, Flatt, Peter and Newsholme, P (2005) L-alanine induces changes in metabolic and signal transduction gene expression in a clonal rat pancreatic beta-cell line and protects from pro-inflammatory cytokine-induced apoptosis. CLINICAL SCIENCE, 109 (5). pp. 447-455. [Journal article]

Green, BD, Liu, HK, McCluskey, Janie, Duffy, NA, O'Harte, Finbarr, McClenaghan, Neville and Flatt, Peter (2005) Function of a long-term, GLP-1-treated, insulin-secreting cell line is improved by preventing DPP IV-mediated degradation of GLP-1. DIABETES OBESITY AND METABOLISM, 7 (5). pp. 563-569. [Journal article]

Ball, AJ, Flatt, Peter and McClenaghan, Neville (2004) Acute and long-term effects of nateglinide on insulin secretory pathways. BRITISH JOURNAL OF PHARMACOLOGY, 142 (2). pp. 367-373. [Journal article]

Ball, AJ, McCluskey, Janie, Flatt, Peter and McClenaghan, Neville (2004) Chronic exposure to tolbutamide and glibenclamide impairs insulin secretion but not transcription of K-ATP channel components. PHARMACOLOGICAL RESEARCH, 50 (1). pp. 41-46. [Journal article]

Dixon, G, Nolan, J, McClenaghan, Neville, Flatt, Peter and Newsholme, P (2004) Arachidonic acid, palmitic acid and glucose are important for the modulation of clonal pancreatic beta-cell insulin secretion, growth and functional integrity. CLINICAL SCIENCE, 106 (2). pp. 191-199. [Journal article]

Liu, HK, Green, BD, Flatt, Peter, McClenaghan, Neville and McCluskey, Janie (2004) Effects of long-term exposure to nicotinamide and sodium butyrate on growth, viability, and the function of clonal insulin secreting cells. ENDOCRINE RESEARCH, 30 (1). pp. 61-68. [Journal article]

Liu, HK, Green, BD, Gault, Victor, McCluskey, Janie, McClenaghan, Neville, O'Harte, Finbarr and Flatt, Peter (2004) N-acetyl-GLP-1: a DPP IV-resistant analogue of glucagon-like peptide-1 (GLP-1) with improved effects on pancreatic beta-cell-associated gene expression. CELL BIOLOGY INTERNATIONAL, 28 (1). pp. 69-73. [Journal article]

Liu, HK, Green, BD, McClenaghan, Neville, McCluskey, Janie and Flatt, Peter (2004) Long-term beneficial effects of vanadate, tungstate, and molybdate on insulin secretion and function of cultured beta cells. PANCREAS, 28 (4). pp. 364-368. [Journal article]

McClenaghan, Neville, McCluskey, Janie, Flatt, Peter and Patterson, Steven (2004) Homocysteine, a metabolic syndrome risk factor, exerts detrimental effects on insulin secretion and pancreatic beta cell function. DIABETOLOGIA, 47 (Suppl. 1). p. 466. [Journal article]

Brennan, L, Corless, M, Hewage, C, Malthouse, JPG, McClenaghan, Neville, Flatt, Peter and Newsholme, P (2003) C-13 NMR analysis reveals a link between L-glutamine metabolism, D-glucose metabolism and gamma-glutamyl cycle activity in a clonal pancreatic beta-cell line. DIABETOLOGIA, 46 (11). pp. 1512-1521. [Journal article]

Dixon, G, Nolan, J, McClenaghan, Neville, Flatt, Peter and Newsholme, P (2003) A comparative study of amino acid consumption by rat islet cells and the clonal beta-cell line BRIN-BD11 - the functional significance of L-alanine. JOURNAL OF ENDOCRINOLOGY, 179 (3). pp. 447-454. [Journal article]

Irwin, Nigel, Green, BD, Lui, HK, McCluskey, Janie, McClenaghan, Neville, Gault, Victor, Harriott, P, Greer, B, O'Harte, Finbarr and Flatt, Peter (2003) Dipeptidylpeptidase IV-resistant glucagon-like peptide-1(7-36)amide analogue N-acetyl-GLP-1 has improved effects on pancreatic beta-cell associated gene expression. Irish Journal of Medical Science, 172 (S1) . p. 24. [Journal article]

Brennan, L, Shine, A, Hewage, C, Malthouse, JPG, Brindle, KM, McClenaghan, Neville, Flatt, Peter and Newsholme, P (2002) A nuclear magnetic resonance-based demonstration of substantial oxidative L-alanine metabolism and L-alanine-enhanced glucose metabolism in a clonal pancreatic beta-cell line - Metabolism of L-alanine is important to the regulation of insulin secretion. DIABETES, 51 (6). pp. 1714-1721. [Journal article]

Conroy, SJ, Green, I, Dixon, G, Byrne, PM, Nolan, J, Abdel-Wahab, Yasser, McClenaghan, Neville, Flatt, Peter and Newsholme, P (2002) Evidence for a sustained increase in clonal beta-cell basal intracellular Ca2+ levels after incubation in the presence of newly diagnosed type-1 diabetic patient sera. Possible role in serum-induced inhibition of insulin secretion. JOURNAL OF ENDOCRINOLOGY, 173 (1). pp. 53-62. [Journal article]

Hamid, M, McCluskey, Janie, McClenaghan, Neville and Flatt, Peter (2002) Comparison of the secretory properties of four insulin-secreting cell lines. ENDOCRINE RESEARCH, 28 (1-2). pp. 35-47. [Journal article]

Picton, SF, McCluskey, Janie, Flatt, Peter and McClenaghan, Neville (2002) Effects of cytotoxic agents on functional integrity and antioxidant enzymes in clonal beta-cells. DIABETES AND METABOLISM, 28 (6, Part 2). S70-S77. [Journal article]

Brennan, L, Shine, A, Hewage, C, Brindle, KM, Malthouse, JPG, McClenaghan, Neville, Flatt, Peter and Newsholme, P (2001) A NMR study of glucose and alanine metabolism by the beta cell lines RINm5F and BRIN-BD11. DIABETOLOGIA, 44 (Suppl. 1). p. 472. [Journal article]

Hamid, M, McCluskey, Janie, McClenaghan, Neville and Flatt, Peter (2001) Comparative functional study of clonal insulin-secreting cells cultured in five commercially available tissue culture media. CELL TRANSPLANTATION, 10 (2). pp. 153-159. [Journal article]

Hamid, M, McCluskey, Janie, McClenaghan, Neville and Flatt, Peter (2001) Functional examination of microencapsulated bioengineered insulin-secreting beta-cells. CELL BIOLOGY INTERNATIONAL, 25 (6). pp. 553-556. [Journal article]

McClenaghan, Neville, Ball, AJ and Flatt, Peter (2001) Nateglinide exhibits glucose-sensitive K-ATP channel-dependent and independent insulinotropic actions. DIABETOLOGIA, 44 (Suppl. 1). p. 824. [Journal article]

McClenaghan, Neville, Ball, AJ and Flatt, Peter (2001) Specific desensitization of sulfonylurea- but not imidazoline-induced insulin release after prolonged tolbutamide exposure. BIOCHEMICAL PHARMACOLOGY, 61 (5). pp. 527-536. [Journal article]

Ball, AJ, Flatt, Peter and McClenaghan, Neville (2000) Desensitization of sulphonylurea- and nutrient-induced insulin secretion following prolonged treatment with glibenclamide. EUROPEAN JOURNAL OF PHARMACOLOGY, 408 (3). pp. 327-333. [Journal article]

Ball, AJ, Flatt, Peter and McClenaghan, Neville (2000) Stimulation of insulin secretion in clonal BRIN-BD11 cells by the imidazoline derivatives KU14R and RX801080. PHARMACOLOGICAL RESEARCH, 42 (6). pp. 575-579. [Journal article]

Ball, AJ, McCluskey, Janie, Flatt, Peter and McClenaghan, Neville (2000) Drug-induced desensitization of insulinotropic actions of sulfonylureas. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 271 (1). pp. 234-239. [Journal article]

Flatt, Peter, Ball, AJ and McClenaghan, Neville (2000) GLP-1(7-36)amide enhances K-ATP channel-dependent and -independent insulinotropic actions of sulphonylureas. DIABETOLOGIA, 43 (Suppl. 1). p. 119. [Journal article]

Hamid, M, McCluskey, Janie, McClenaghan, Neville and Flatt, Peter (2000) Culture and function of electrofusion-derived clonal insulin-secreting cells immobilized on solid and macroporous microcarrier beads. BIOSCIENCE REPORTS, 20 (3). pp. 167-176. [Journal article]

McClenaghan, Neville, Ball, AJ and Flatt, Peter (2000) Induced desensitization of the insulinotropic effects of antidiabetic drugs, BTS 67 582 and tolbutamide. BRITISH JOURNAL OF PHARMACOLOGY, 130 (2). pp. 478-484. [Journal article]

McClenaghan, Neville and Flatt, Peter (2000) Metabolic and K-ATP channel-independent actions of keto acid initiators of insulin secretion. PANCREAS, 20 (1). pp. 38-46. [Journal article]

Ball, AJ, Flatt, Peter and McClenaghan, Neville (1999) BTS 67 582 has common and distinct beta cell actions to sulphonylurea and imidazoline drugs. DIABETOLOGIA, 42 (Suppl. 1). p. 919. [Journal article]

Chapman, JC, McClenaghan, Neville, Cosgrove, KE, Hashmi, MN, Shepherd, RM, Giesberts, AN, White, SJ, Ammala, C, Flatt, Peter and Dunne, MJ (1999) ATP-sensitive potassium channels and efaroxan-induced insulin release in the electrofusion-derived BRIN-BD11 beta-cell line. DIABETES, 48 (12). pp. 2349-2357. [Journal article]

Dunne, MJ, Chapman, JC, McClenaghan, Neville, Hashmi, MN, Shepherd, RM, Cosgrove, KE, Giesberts, AN, White, SJ and Flatt, Peter (1999) The imidazoline efaroxan influences SUR1 protein expression in insulin-secreting cells. DIABETOLOGIA, 42 (Suppl. 1). p. 483. [Journal article]

McClenaghan, Neville, Ball, AJ and Flatt, Peter (1999) Downregulation of K-ATP-channel-dependent and -independent insulinotropic actions of tolbutamide. DIABETOLOGIA, 42 (Suppl. 1). p. 479. [Journal article]

McClenaghan, Neville and Flatt, Peter (1999) Engineering cultured insulin-secreting pancreatic B-cell lines. JOURNAL OF MOLECULAR MEDICINE-JMM, 77 (1). pp. 235-243. [Journal article]

McClenaghan, Neville and Flatt, Peter (1999) Glucose and non-glucidic nutrients exert permissive effects on 2-keto acid regulation of pancreatic beta-cell function. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1426 (1). pp. 110-118. [Journal article]

McClenaghan, Neville and Flatt, Peter (1999) Physiological and pharmacological regulation of insulin release: insights offered through exploitation of insulin-secreting cell lines. DIABETES OBESITYAND METABOLISM, 1 (3). pp. 137-150. [Journal article]

McClenaghan, Neville, Barnett, CR and Flatt, Peter (1998) Na+ cotransport by metabolizable and nonmetabolizable amino acids stimulates a glucose-regulated insulin-secretory response. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 249 (2). pp. 299-303. [Journal article]

McClenaghan, Neville and Flatt, Peter (1998) Metabolic and K+-ATP channel-independent secretory actions of glucose and 2-keto acids in clonal beta-cells. DIABETOLOGIA, 41 (Suppl. 1). p. 545. [Journal article]

McClenaghan, Neville, Flatt, Peter and Bailey, CJ (1998) Insulin-releasing action of the novel antidiabetic agent BTS 67 582. BRITISH JOURNAL OF PHARMACOLOGY, 123 (3). pp. 400-404. [Journal article]

Chapman, JC, Cosgrove, K, McClenaghan, Neville, Ammala, C, Flatt, Peter and Dunne, MJ (1997) Properties of ion channels and the regulation of insulin secretion in the novel glucose-responsive beta-cell line, BRIN-BD11. DIABETOLOGIA, 40 (Suppl. 1). p. 390. [Journal article]

Abdel-Wahab, Yasser, O'Harte, Finbarr, Ratcliff, H, McClenaghan, Neville, Barnett, CR and Flatt, Peter (1996) Glycation of insulin in the islets of Langerhans of normal and diabetic animals. DIABETES, 45 (11). pp. 1489-1496. [Journal article]

McClenaghan, Neville, Barnett, CR, AhSing, E, Abdel-Wahab, Yasser, O'Harte, Finbarr, Yoon, TW, SwanstonFlatt, SK and Flatt, Peter (1996) Characterization of a novel glucose-responsive insulin-secreting cell line, BRIN-BD11, produced by electrofusion. DIABETES, 45 (8). pp. 1132-1140. [Journal article]

McClenaghan, Neville, Barnett, CR, AhSing, E, SwanstonFlatt, SK and Flatt, Peter (1996) Secretory properties of clonal insulin-secreting BRIN-BG5 cells, produced by electrofusion. BIOCHEMICAL SOCIETY TRANSACTIONS, 24 (1). S101. [Journal article]

McClenaghan, Neville, Barnett, CR and Flatt, Peter (1996) Na+ involvement in glucose and neutral amino acid-induced insulin secretion. DIABETOLOGIA, 39 (Suppl. 1). p. 424. [Journal article]

McClenaghan, Neville, Barnett, CR, O'Harte, Finbarr and Flatt, Peter (1996) Mechanisms of amino acid-induced insulin secretion from the glucose-responsive BRIN-BD11 pancreatic B-cell line. JOURNAL OF ENDOCRINOLOGY, 151 (3). pp. 349-357. [Journal article]

McClenaghan, Neville, Barnett, CR, O'Harte, Finbarr, SwanstonFlatt, SK, AhSing, E and Flatt, Peter (1996) Characteristics of BRIN-BG5 and BRIN-BG7, two novel glucose-responsive insulin-secreting cell lines produced by electrofusion. JOURNAL OF ENDOCRINOLOGY, 148 (3). pp. 409-417. [Journal article]

McClenaghan, Neville, Gallagher, Alison, Barnett, CR and Flatt, Peter (1996) Hexose recognition by insulin-secreting BRIN-BD11 cells. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 223 (3). pp. 724-728. [Journal article]

Rasschaert, J, Flatt, Peter, Barnett, CR, McClenaghan, Neville and Malaisse, WJ (1996) D-glucose metabolism in BRIN-BD11 islet cells. BIOCHEMICAL AND MOLECULAR MEDICINE, 57 (2). pp. 97-105. [Journal article]

Rasschaert, J, Flatt, Peter, McClenaghan, Neville and Malaisse, WJ (1996) Amino acid oxidation in BRIN-BD11 islet cells. MEDICAL SCIENCE RESEARCH, 24 (10). pp. 691-692. [Journal article]

Barnett, CR, Clarke, J, McClenaghan, Neville and Flatt, Peter (1995) CYTOCHROME-P450 CYP1A EXPRESSION IN THE PANCREATIC-ISLETS OF LANGERHANS. DIABETOLOGIA, 38 (Suppl. 1). A135. [Journal article]

Clarke, J, McClenaghan, Neville, Barnett, CR, Ahsing, E, Yoon, TW, Swanstonflatt, SK and Flatt, Peter (1995) BRIN-BG7, A NOVEL GLUCOSE-RESPONSIVE INSULIN-SECRETING CELL-LINE PRODUCED BY ELECTROFUSION. DIABETOLOGIA, 38 (Suppl. 1). A108. [Journal article]

Flatt, Peter, O'Harte, Finbarr, Abdel-Wahab, Yasser, McClenaghan, Neville and Barrnett, CR (1995) GLYCATION OF INSULIN AND PROINSULIN OCCURS IN THE ISLETS OF LANGERHANS OF DIABETIC ANIMALS. DIABETOLOGIA, 38 (Suppl. 1). A92. [Journal article]

McClenaghan, Neville, Barnett, CR, Swanstonflatt, SK and Flatt, Peter (1995) COMPARISON OF THE GLUCOSE-SENSING ABILITY OF 3 NOVEL GLUCOSE-RESPONSIVE PANCREATIC B-CELL LINES. DIABETOLOGIA, 38 (Suppl. 1). A108. [Journal article]

McClenaghan, Neville, Yoon, TW, Barnett, CR, Wilson, AM, Abdel-Wahab, Yasser, Swanstonflatt, S, Ahsing, E and Flatt, Peter (1994) EFFECT OF GLUCOSE AND AMINO-ACIDS ON INSULIN-SECRETION FROM A NOVEL PANCREATIC B-CELL LINE PRODUCED BY ELECTROFUSION. BIOCHEMICAL SOCIETY TRANSACTIONS, 22 (2). S237. [Journal article]

Flatt, Peter, Yoon, TW, Barnett, CR, McClenaghan, Neville, Wilson, AM, Abdel-Wahab, Yasser, Ahsing, E and Swanstonflatt, SK (1993) PRODUCTION OF A NOVEL GLUCOSE-RESPONSIVE INSULIN-SECRETING PANCREATIC B-CELL LINE BY ELECTROFUSION. DIABETOLOGIA, 36 (Suppl. 1). A31. [Journal article]

McClenaghan, Neville, BERTS, A, DRYSELIUS, S, THORELL, IM and HELLMAN, B (1992) NONMETABOLIZABLE ALPHA-AMINOISOBUTYRIC-ACID EVOKES A GLUCOSE-DEPENDENT INSULIN SECRETORY RESPONSE IN BETA-CELLS. DIABETOLOGIA, 35 (Suppl. 1). A113. [Journal article]

TENGHOLM, A, McClenaghan, Neville, GRAPENGIESSER, E, GYLFE, E and HELLMAN, B (1992) GLYCINE POTENTIATION OF INSULIN RELEASE INVOLVES NA+-DEPENDENT INCREASE OF CYTOPLASMIC CA2+. DIABETOLOGIA, 35 (Suppl. 1). A117. [Journal article]

TENGHOLM, A, McClenaghan, Neville, GRAPENGIESSER, E, GYLFE, E and HELLMAN, B (1992) GLYCINE TRANSFORMATION OF CA-2+ OSCILLATIONS INTO A SUSTAINED INCREASE PARALLELS POTENTIATION OF INSULIN RELEASE. BIOCHIMICA ET BIOPHYSICA ACTA, 1137 (3). pp. 243-247. [Journal article]

This list was generated on Sat Apr 19 07:31:22 2014 BST.