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Number of items: 41.

Journal article

Vasu, S, McClenaghan, Neville, McCluskey, Janie and Flatt, Peter (2013) Cellular responses of novel human pancreatic β-cell line, 1.1B4 to hyperglycemia. Islets, 5 (4). 0-0. [Journal article]

Vasu, S, McClenaghan, Neville, McCluskey, Janie and Flatt, Peter (2013) Effects of lipotoxicity on novel insulin secreting human pancreatic β-cell line, 1.1B4. Biological Chemistry, 394 (7). pp. 909-918. [Journal article]

Vasu, S, Moffett, RC, McCluskey, Janie, Hamid, MH, Irwin, Nigel and Flatt, Peter (2013) Beneficial effects of parenteral GLP-1 delivery by cell therapy in insulin-deficient streptozotocin diabetic mice. Gene Therapy, 20 (11). pp. 1077-1084. [Journal article]

Vasu, Srividya, McClenaghan, Neville, McCluskey, Janie and Flatt, Peter (2013) Mechanisms of toxicity by proinflammatory cytokines in a novel human pancreatic beta cell line, 1.1B4. Biochimica et Biophysica Acta , 1840 (1). pp. 136-145. [Journal article]

Guo-Parke, H, McCluskey, Janie, Kelly , C, Hamid , M, McClenaghan, Neville and Flatt, Peter (2012) Configuration of electrofusion-derived human insulin-secreting cell line as pseudoislets enhances functionality and therapeutic utility. Journal of Endocrinology , 214 (3). pp. 257-265. [Journal article]

Guo-Parke, H., McCluskey, Janie, Kelly, Catriona, Hamid, M., McClenaghan, Neville and Flatt, Peter (2012) Configuration of electrofusion-derived human insulin-secreting cell line as pseudoislets enhances functionality and therapeutic utility. Journal of Endocrinology, 214 (3). p. 257. [Journal article]

McCluskey, Janie, Hamid, Muhajir, Guo-Parke, Hong, McClenaghan, Neville, Gomis, Ramon and Flatt, Peter (2011) Development and Functional Characterization of Insulin-releasing Human Pancreatic Beta Cell Lines Produced by Electrofusion. JOURNAL OF BIOLOGICAL CHEMISTRY, 286 (25). pp. 21982-21992. [Journal article]

Kelly, C., Parke, H. Guo, McCluskey, Janie, Flatt, Peter and McClenaghan, Neville (2010) Evaluation of role of islet cell paracrine interactions in regulation of insulin secretion using a new heterotypic pseudoislet model. REGULATORY PEPTIDES, 164 (1, Sp. Iss. SI). p. 33. [Journal article]

Kelly, Catriona, Guo, Hong, McCluskey, Janie, Flatt, Peter and McClenaghan, Neville (2010) Comparison of Insulin Release From MIN6 Pseudoislets and Pancreatic Islets of Langerhans Reveals Importance of Homotypic Cell Interactions. PANCREAS, 39 (7). pp. 1016-1023. [Journal article]

Kelly, Catriona, Guo, Hong, McCluskey, Janie, Flatt, Peter and McClenaghan, Neville (2010) Comparison of Insulin Release From MIN6 Pseudoislets and Pancreatic Islets of Langerhans Reveals Importance of Homotypic Cell Interactions. Pancreas, 39 (7). p. 1016. [Journal article]

Kelly, Catriona, Parke, Hong Guo, McCluskey, Janie, Flatt, Peter and McClenaghan, Neville (2010) The role of glucagon- and somatostatin-secreting cells in the regulation of insulin release and beta-cell function in heterotypic pseudoislets. DIABETES-METABOLISM RESEARCH AND REVIEWS, 26 (7). pp. 525-533. [Journal article]

Kelly, Catriona, Parke, Hong Guo, McCluskey, Janie, Flatt, Peter and McClenaghan, Neville (2010) The role of glucagon- and somatostatin-secreting cells in the regulation of insulin release and beta-cell function in heterotypic pseudoislets. Diabetes/Metabolism Research and Reviews, 26 (7). p. 525. [Journal article]

McCluskey, Janie, Vasu, S., Hamid, M. H., Irwin, Nigel and Flatt, Peter (2010) Functional analysis of the GLP-1 secreting GLUTag cell line in vitro and in normal and diabetic SCID mice. IRISH JOURNAL OF MEDICAL SCIENCE, 179 (Suppl. 13). p. 537. [Journal article]

Vasu, S., Hamid, M. H., McCluskey, Janie, Irwin, Nigel and Flatt, Peter (2010) Implantation of GLP-1 secreting cells fails to recapitulate effects of exogenous GLP-1 mimetics in mice. REGULATORY PEPTIDES, 164 (1, Sp. Iss. SI). p. 32. [Journal article]

Liu, Hui-Kang, McCluskey, Janie, McClenaghan, Neville and Flatt, Peter (2008) Iterative exposure of clonal BRIN-BD11 cells to ninhydrin enables selection of robust toxin-resistant cells but with decreased gene expression of insulin secretory function. PANCREAS, 36 (3). pp. 294-301. [Journal article]

McClean, Paula, Gault, Victor, Irwin, Nigel, McCluskey, Janie and Flatt, Peter (2008) Daily administration of the GIP-R antagonist (Pro(3))GIP in streptozotocin-induced diabetes suggests that insulin-dependent mechanisms are critical to anti-obesity-diabetes actions of (Pro(3))GIP. DIABETES OBESITY AND METABOLISM, 10 (4). pp. 336-342. [Journal article]

Gault, Victor, McClean, Paula, Irwin, Nigel, McCluskey, Janie and Flatt, Peter (2007) Effects of GIP-receptor antagonism in a streptozotocin-induced model of insulin deficiency. DIABETIC MEDICINE, 24 (Suppl. 1). p. 40. [Journal article]

Gault, Victor, McClean, Paula, Irwin, Nigel, Power, Gavin J., McCluskey, Janie and Flatt, Peter (2007) Effects of subchronic treatment with the long-acting glucose-dependent insulinotropic polypeptide receptor agonist, N-AcGIP, on glucose homeostasis in Streptozotocin-induced diabetes. PANCREAS, 35 (1). pp. 73-79. [Journal article]

Liu, Hui-Kang, McCluskey, Janie, McClenaghan, Neville and Flatt, Peter (2007) Streptozotocin-resistant BRIN-BD11 cells possess wide spectrum of toxin tolerance and enhanced insulin-secretory capacity. ENDOCRINE, 32 (1). pp. 20-29. [Journal article]

McClean, Paula, Gault, Victor, Irwin, Nigel, Power, G. J., McCluskey, Janie and Flatt, Peter (2007) Effects of daily administration of the glucose-dependent insulinotropic polypeptide (GIP) receptor agonist, N-Acetyl-GIP, in streptozotocin-incluced diabetic mice. DIABETIC MEDICINE, 24 (Suppl. 1). pp. 40-41. [Journal article]

Patterson, Steven, Scullion, Siobhan M. J., McCluskey, Janie, Flatt, Peter and McClenaghan, Neville (2007) Prolonged exposure to homocysteine results in diminished but reversible pancreatic beta-cell responsiveness to insulinotropic agents. DIABETES-METABOLISM RESEARCH AND REVIEWS, 23 (4). pp. 324-334. [Journal article]

Liu, Hui-Kang, Green, Brian D., McClenaghan, Neville, McCluskey, Janie and Flatt, Peter (2006) Deleterious effects of supplementation with dehydroepiandrosterone sulphate or dexamethasone on rat insulin-secreting cells under in vitro culture condition. BIOSCIENCE REPORTS, 26 (1). pp. 31-38. [Journal article]

Marenah, Lamin, McCluskey, Janie, Abdel-Wahab, Yasser, O'Harte, Finbarr, McClenaghan, Neville and Flatt, Peter (2006) A stable analogue of glucose-dependent insulinotropic polypeptide, GIP(LysPAL(16)), enhances functional differentiation of mouse embryonic stem cells into cells expressing islet-specific genes and hormones. BIOLOGICAL CHEMISTRY, 387 (7). pp. 941-947. [Journal article]

Gault, Victor, Irwin, Nigel, Green, BD, McCluskey, Janie, Greer, B, Bailey, CJ, Harriott, P, O'Harte, Finbarr and Flatt, Peter (2005) Chemical ablation of gastric inhibitory polypeptide receptor action by daily (Pro(3))GIP administration improves glucose tolerance and ameliorates insulin resistance and abnormalities of islet structure in obesity-related diabetes. DIABETES, 54 (8). pp. 2436-2446. [Journal article]

Green, BD, Liu, HK, McCluskey, Janie, Duffy, NA, O'Harte, Finbarr, McClenaghan, Neville and Flatt, Peter (2005) Function of a long-term, GLP-1-treated, insulin-secreting cell line is improved by preventing DPP IV-mediated degradation of GLP-1. DIABETES OBESITY AND METABOLISM, 7 (5). pp. 563-569. [Journal article]

Ball, AJ, McCluskey, Janie, Flatt, Peter and McClenaghan, Neville (2004) Chronic exposure to tolbutamide and glibenclamide impairs insulin secretion but not transcription of K-ATP channel components. PHARMACOLOGICAL RESEARCH, 50 (1). pp. 41-46. [Journal article]

Irwin, Nigel, Gault, Victor, Green, BD, Greer, B, McCluskey, Janie, Harriott, P, O'Harte, Finbarr and Flatt, Peter (2004) Effects of short-term chemical ablation of the GIP receptor on insulin secretion, islet morphology and glucose homeostasis in mice. BIOLOGICAL CHEMISTRY, 385 (9). pp. 845-852. [Journal article]

Liu, HK, Green, BD, Flatt, Peter, McClenaghan, Neville and McCluskey, Janie (2004) Effects of long-term exposure to nicotinamide and sodium butyrate on growth, viability, and the function of clonal insulin secreting cells. ENDOCRINE RESEARCH, 30 (1). pp. 61-68. [Journal article]

Liu, HK, Green, BD, Gault, Victor, McCluskey, Janie, McClenaghan, Neville, O'Harte, Finbarr and Flatt, Peter (2004) N-acetyl-GLP-1: a DPP IV-resistant analogue of glucagon-like peptide-1 (GLP-1) with improved effects on pancreatic beta-cell-associated gene expression. CELL BIOLOGY INTERNATIONAL, 28 (1). pp. 69-73. [Journal article]

Liu, HK, Green, BD, McClenaghan, Neville, McCluskey, Janie and Flatt, Peter (2004) Long-term beneficial effects of vanadate, tungstate, and molybdate on insulin secretion and function of cultured beta cells. PANCREAS, 28 (4). pp. 364-368. [Journal article]

McClenaghan, Neville, McCluskey, Janie, Flatt, Peter and Patterson, Steven (2004) Homocysteine, a metabolic syndrome risk factor, exerts detrimental effects on insulin secretion and pancreatic beta cell function. DIABETOLOGIA, 47 (Suppl. 1). p. 466. [Journal article]

McCluskey, Janie, Irwin, Nigel, Gault, Victor, Green, BD, Flatt, Peter and O'Harte, Finbarr (2004) Longer-term ablation of GIP signalling in normal mice demonstrates importance of GIP for glucose homeostasis as part of the enteroinsular axis. Proceedings of the EASD Islet Study Group, Meeting on Molecular Aspects of Pancreatic Islet Function, 1 . p. 26. [Journal article]

Hunter, SJ, Boyd, AC, O'Harte, Finbarr, McKillop, Aine, Wiggam, MI, Mooney, MH, McCluskey, Janie, Lindsay, JR, Ennis, CN, Gamble, R, Sheridan, B, Barnett, CR, McNulty, Helene, Bell, PM and Flatt, Peter (2003) Demonstration of glycated insulin in human diabetic plasma and decreased biological activity assessed by euglycemic-hyperinsulinemic clamp technique in humans. DIABETES, 52 (2). pp. 492-498. [Journal article]

Irwin, Nigel, Green, BD, Lui, HK, McCluskey, Janie, McClenaghan, Neville, Gault, Victor, Harriott, P, Greer, B, O'Harte, Finbarr and Flatt, Peter (2003) Dipeptidylpeptidase IV-resistant glucagon-like peptide-1(7-36)amide analogue N-acetyl-GLP-1 has improved effects on pancreatic beta-cell associated gene expression. Irish Journal of Medical Science, 172 (S1) . p. 24. [Journal article]

Hamid, M, McCluskey, Janie, McClenaghan, Neville and Flatt, Peter (2002) Comparison of the secretory properties of four insulin-secreting cell lines. ENDOCRINE RESEARCH, 28 (1-2). pp. 35-47. [Journal article]

Picton, SF, McCluskey, Janie, Flatt, Peter and McClenaghan, Neville (2002) Effects of cytotoxic agents on functional integrity and antioxidant enzymes in clonal beta-cells. DIABETES AND METABOLISM, 28 (6, Part 2). S70-S77. [Journal article]

Hamid, M, McCluskey, Janie, McClenaghan, Neville and Flatt, Peter (2001) Comparative functional study of clonal insulin-secreting cells cultured in five commercially available tissue culture media. CELL TRANSPLANTATION, 10 (2). pp. 153-159. [Journal article]

Hamid, M, McCluskey, Janie, McClenaghan, Neville and Flatt, Peter (2001) Functional examination of microencapsulated bioengineered insulin-secreting beta-cells. CELL BIOLOGY INTERNATIONAL, 25 (6). pp. 553-556. [Journal article]

Ball, AJ, McCluskey, Janie, Flatt, Peter and McClenaghan, Neville (2000) Drug-induced desensitization of insulinotropic actions of sulfonylureas. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 271 (1). pp. 234-239. [Journal article]

Hamid, M, McCluskey, Janie, McClenaghan, Neville and Flatt, Peter (2000) Culture and function of electrofusion-derived clonal insulin-secreting cells immobilized on solid and macroporous microcarrier beads. BIOSCIENCE REPORTS, 20 (3). pp. 167-176. [Journal article]

McKillop, Aine, McCluskey, Janie, Boyd, AC, Mooney, MH, Flatt, Peter and O'Harte, Finbarr (2000) Production and characterization of specific antibodies for evaluation of glycated insulin in plasma and biological tissues. JOURNAL OF ENDOCRINOLOGY, 167 (1). pp. 153-163. [Journal article]

This list was generated on Thu Apr 24 06:47:34 2014 BST.