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Number of items: 53.

Journal article

Moran, BM, Abdel-Wahab, Yasser, Flatt, Peter and Mckillop, Aine (2014) Activation of GPR119 by fatty acid agonists augments insulin release from clonal β-cells and isolated pancreatic islets and improves glucose tolerance in mice. Biological Chemistry, 395 (4). pp. 453-464. [Journal article]

Mckillop, Aine, Moran, BM, Abdel-Wahab, Yasser and Flatt, Peter (2013) Evaluation of the insulin releasing and antihyperglycaemic activities of GPR55 lipid agonists using clonal beta-cells, isolated pancreatic islets and mice. British Journal of Pharmacology, 170 (5). pp. 978-990. [Journal article]

Mckillop, Aine and Flatt, Peter (2011) Emerging Applications of Metabolomic and Genomic Profiling in Diabetic Clinical Medicine. DIABETES CARE, 34 (12). pp. 2624-2630. [Journal article]

Mckillop, Aine, Ng, MT, Flatt, Peter and Abdel-Wahab, Yasser (2011) Autocrine inhibitory effects of proinsulin C-peptide and insulin on insulin secretion and pancreatic beta cell function. Diabetologia, 54 . S258. [Journal article]

McKillop, Aine, Ng, MT, Flatt, Peter and Abdel-Wahab, Yasser (2010) Involvement of proinsulin C-peptide in the regulation of pancreatic beta cell function and glucose homeostasis. REGULATORY PEPTIDES, 164 (1, Sp. Iss. SI). p. 43. [Journal article]

Mckillop, Aine, Ng, MT, Flatt, Peter and Abdel-Wahab, Yasser (2010) Regulatory role for proinsulin C-peptide in pancreatic beta cell function and glucose homeostasis. Irish Journal of Medical Science, 179 . p. 83. [Journal article]

Taylor, Ashley, Irwin, Nigel, McKillop, Aine, Flatt, Peter and Gault, Victor (2010) Xenin: An anorectic peptide involved in insulin secretion and glucose homeostasis. REGULATORY PEPTIDES, 164 (1, Sp. Iss. SI). p. 41. [Journal article]

Taylor, Ashley, Irwin, Nigel, McKillop, Aine, Patterson, Steven, Flatt, Peter and Gault, Victor (2010) Evaluation of the degradation and metabolic effects of the gut peptide xenin on insulin secretion, glycaemic control and satiety. JOURNAL OF ENDOCRINOLOGY, 207 (1). pp. 87-93. [Journal article]

McKillop, Aine, Duffy, NA, Lindsay, JR, Green, BD, Patterson, Steven, O'Harte, Finbarr, Bell, PM and Flatt, Peter (2009) Insulinotropic actions of nateglinide in type 2 diabetic patients and effects on dipeptidyl peptidase-IV activity and glucose-dependent insulinotropic polypeptide degradation. European Journal of Endocrinology, 16 (6). pp. 877-885. [Journal article]

Mckillop, Aine, Ng, MT, Flatt, Peter and Abdel-Wahab, Yasser (2009) Evidence for inhibitory autocrine effects of proinsulin C-peptide on pancreatic beta cell function and insulin secretion. DIABETOLOGIA, 52 (Suppl. 1). p. 406. [Journal article]

Mckillop, Aine, Ng, MT, Flatt, Peter and Abdel-Wahab, Yasser (2009) Evidence for inhibitory autocrine effects of proinsulin C-peptide on pancreatic beta cell function and insulin secretion. DIABETOLOGIA , 52 . S167-S167. [Journal article]

Ng, MT, Abdel-Wahab, Yasser, Flatt, Peter and Mckillop, Aine (2009) Autocrine effects of C-peptide on pancreatic beta cell function and insulin secretion in BRIN-BD11 cells and isolated islets. Irish Journal of Medical Science, 178 . S391. [Journal article]

Taylor, AI, Frizzell, N, McKillop, Aine, Flatt, Peter and Gault, Victor (2009) Effect of RU486 on hepatic and adipocyte gene expression improves diabetes control in obesity-type 2 diabetes. Hormone Metabolic Research , 41 (12). pp. 899-904. [Journal article]

McKillop, Aine, Duffy, Nicola A, Lindsay, John R, O'Harte, Finbarr, Bell, Patrick M and Flatt, Peter (2008) Decreased dipeptidyl peptidase-IV activity and glucagon-like peptide-1(7-36)amide degradation in type 2 diabetic subjects. DIABETES RESEARCH AND CLINICAL PRACTICE, 79 (1). pp. 79-85. [Journal article]

McKillop, Aine and Flatt, Peter (2008) Recent developments in the search for biomarkers for the diagnosis and monitoring of diabetes. Recent Patents on Endocrine, Metabolic & Immune Drug Discovery, 2 (3). pp. 172-177. [Journal article]

Taylor, Ashley, Irwin, Nigel, McKillop, Aine, Flatt, Peter and Gault, Victor (2008) Sub-chronic administration of the 11 beta-HSD1 inhibitor, carbenoxolone, improves glucose tolerance and insulin sensitivity in mice with diet-induced obesity. BIOLOGICAL CHEMISTRY, 389 (4). pp. 441-445. [Journal article]

Doherty, Margaret, Patterson, Steven, Abdel-Wahab, Yasser and Mckillop, Aine (2007) Characterisation and detection of the insulinotropic hormones, GIP and GLP-1 in type 2 diabetes. Irish Journal of Medical Science, 171 . p. 37. [Journal article]

Duffy, Nicola A, Green, Brian D, Irwin, Nigel, Gault, Victor, McKillop, Aine, O'Harte, Finbarr and Flatt, Peter (2007) Effects of antidiabetic drugs on dipeptidyl peptidase IV activity: Nateglinide is an inhibitor of DPP IV and augments the antidiabetic activity of glucagon-like peptide-1. EUROPEAN JOURNAL OF PHARMACOLOGY, 568 (1-3). pp. 278-286. [Journal article]

Gault, Victor, Taylor, AI, Irwin, Nigel, McKillop, Aine and Flatt, Peter (2007) Effects of 11 beta-hydroxysteroid dehydrogenase inhibition on body weight and glucose homeostasis in mice with diet-induced obesity. DIABETOLOGIA, 50 (Suppl. 1). 0659. [Journal article]

Gault, Victor, Taylor, AI, Irwin, Nigel, McKillop, Aine and Flatt, Peter (2007) Metabolic effects of 11beta-hydroxysteroid dehydrogenase inhibition in an animal model of diet-induced obesity. Irish Journal of Medical Science , 176 (S9) . p. 382. [Journal article]

McKillop, Aine, Duffy, NA, Green, BD, Irwin, Nigel, Gault, Victor, O'Harte, Finbarr and Flatt, Peter (2007) Antidiabetic action of nateglinide includes augmentation of glucagon-like peptide-1 activity mediated partly through inhibition of DPP IV mediated degradation. DIABETOLOGIA, 50 (Suppl. 1). 0882. [Journal article]

Mckillop, Aine, Duffy, Nicola, Lindsay, John, Green, Brian, O'Harte, Finbarr, Bell, Patrick and Flatt, Peter (2007) Effects of nateglinide on DPP-IV activity and incretin hormone degradation in type 2 diabetic patients. Irish Journal of Medical Science, 176 . S367. [Journal article]

McKillop, Aine, Duffy, NA, Lindsay, JR, Green, BD, O'Harte, Finbarr, Bell, PM and Flatt, Peter (2006) Insulinotropic actions of nateglinide are accompanied by inhibition of dipeptidyl peptidase-IV activity. DIABETOLOGIA, 49 (Suppl. 1). 0796. [Journal article]

McKillop, Aine, Lindsay, JR, Au, S, Mahood, KI, O'Harte, Finbarr, Flatt, Peter and Bell, PM (2006) Meal-dependent regulation of circulating glycated insulin in type 2 diabetic subjects. HORMONE AND METABOLIC RESEARCH, 38 (2). pp. 94-97. [Journal article]

Lindsay, JR, Duffy, NA, McKillop, Aine, Ardill, J, O'Harte, Finbarr, Flatt, Peter and Bell, PM (2005) Inhibition of dipeptidyl peptidase IV activity by oral metformin in Type 2 diabetes. DIABETIC MEDICINE, 22 (5). pp. 654-657. [Journal article]

McKillop, Aine, Duffy, N, Lindsay, JR, Flatt, Peter, Bell, PM and O'Harte, Finbarr (2004) Decreased dipeptidyl peptidase-IV activity and degradation of glucagon-like peptide-1(7-36)amide in Type 2 diabetes. DIABETOLOGIA, 47 (Suppl. 1). p. 792. [Journal article]

Mckillop, Aine, Lindsay, John, O'Harte, Finbarr, Bell, Patrick and Flatt, Peter (2004) Meal and glucose-dependent insulinotropic polypeptide regulation of circulating glycated insulin in type 2 diabetic subjects. Diabetic Medicine, 21 . pp. 6-7. [Journal article]

Hunter, SJ, Boyd, AC, O'Harte, Finbarr, McKillop, Aine, Wiggam, MI, Mooney, MH, McCluskey, Janie, Lindsay, JR, Ennis, CN, Gamble, R, Sheridan, B, Barnett, CR, McNulty, Helene, Bell, PM and Flatt, Peter (2003) Demonstration of glycated insulin in human diabetic plasma and decreased biological activity assessed by euglycemic-hyperinsulinemic clamp technique in humans. DIABETES, 52 (2). pp. 492-498. [Journal article]

Lindsay, John, Duffy, Nicola, Mckillop, Aine, Ardill, Joy, O'Harte, Finbarr, Flatt, Peter and Bell, Patrick (2003) Inhibition of dipeptidyl peptidase IV (DPP-IV) activity by oral metformin in type 2 diabetes. Diabetic Medicine, 20 . pp. 4-5. [Journal article]

Lindsay, JR, McKillop, Aine, Mooney, MH, Flatt, Peter, Bell, PM and O'Harte, Finbarr (2003) Meal-induced 24-hour profile of circulating glycated insulin in type 2 diabetic subjects measured by a novel radioimmunoassay. METABOLISM-CLINICAL AND EXPERIMENTAL, 52 (5). pp. 631-635. [Journal article]

Lindsay, JR, McKillop, Aine, Mooney, MH, O'Harte, Finbarr, Bell, PM and Flatt, Peter (2003) Demonstration of increased concentrations of circulating glycated insulin in human Type 2 diabetes using a novel and specific radioimmunoassay. DIABETOLOGIA, 46 (4). pp. 475-478. [Journal article]

Lindsay, JR, McKillop, Aine, Mooney, MH, O'Harte, Finbarr, Flatt, Peter and Bell, PM (2003) Effects of nateglinide on the secretion of glycated insulin and glucose tolerance in type 2 diabetes. DIABETES RESEARCH AND CLINICAL PRACTICE, 61 (3). pp. 167-173. [Journal article]

Mckillop, Aine, Duffy, Nicola, Lindsay, John, O'Harte, Finbarr and Flatt, Peter (2003) Decreased activity of dipeptidyl peptidase-IV potentially enhances glucagon-like peptide-1(7-36)amide and gastric inhibitory polypeptide. Diabetic Medicine, 20 . p. 37. [Journal article]

McKillop, Aine, Meade, A, Flatt, Peter and O'Harte, Finbarr (2003) Evaluation of the site(s) of glycation in human proinsulin by ion-trap LCQ electrospray ionization mass spectrometry. REGULATORY PEPTIDES, 113 (1-3). pp. 1-8. [Journal article]

Mckillop, Aine, O'Hare, Mairead, Craig, John and Halliday , Henry (2003) Analysis of the C-terminal region of the molecular forms of human milk bile salt stimulated lipase. Acta Paediatr, 92 . pp. 1-7. [Journal article]

Lindsay, John, Duffy, Nicola, Mckillop, Aine, Ardill, Joy, O'Harte, Finbarr, Flatt, Peter and Bell, Patrick (2002) Metformin inhibits dipeptidyl peptidase IV activity in type 2 diabetes. Irish Journal of Medical Science, 171 . p. 29. [Journal article]

Lindsay, John, Mckillop, Aine, Mooney, Mark, O'Harte, Finbarr, Bell, Patrick and Flatt, Peter (2002) Elevated plasma glycated insulin in type 2 diabetes, detected using a novel radioimmunoassay. Diabetic Medicine, 19 . p. 182. [Journal article]

Lindsay, John, Mckillop, Aine, Mooney, Mark, O'Harte, Finbarr, Flatt, Peter and Bell, Patrick (2002) Demonstration of diurnal variation of plasma glycated insulin in type 2 diabetes. Endocrine Abstracts, 3 . p. 85. [Journal article]

McKillop, Aine, Abdel-Wahab, Yasser, Mooney, MH, O'Harte, Finbarr and Flatt, Peter (2002) Secretion of glycated insulin from pancreatic beta-cells in diabetes represents a novel aspect of beta-cell dysfunction and glucose toxicity. DIABETES AND METABOLISM, 28 (6, Part 2). S61-S69. [Journal article]

Mckillop, Aine, Lindsay, John, Mooney, Mark, Flatt, Peter, Bell, John and O'Harte, Finbarr (2002) Detection, isolation and fluctuation of glycated insulin in type 2 diabetic subjects. Irish Journal of Medical Science, 171 . p. 31. [Journal article]

McKillop, Aine, Lindsay, JR, Mooney, MH, O'Harte, Finbarr, Bell, PM and Flatt, Peter (2002) Electrospray ionization mass spectrometry characterisation and measurement of circulating glycated insulin and responses to fasting and feeding in Type 2 diabetic subjects. DIABETOLOGIA, 45 (Suppl. 2). p. 1221. [Journal article]

Mooney, MH, Abdel-Wahab, Yasser, McKillop, Aine, O'Harte, Finbarr and Flatt, Peter (2002) Evaluation of glycated glucagon-like peptide-1(7-36)amide in intestinal tissue of normal and diabetic animal models. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1569 (1-3). pp. 75-80. [Journal article]

Lindsay, John, Mckillop, Aine, Mooney, Mark, O'Harte, Finbarr, Flatt, Peter and Bell, Patrick (2001) Detection of glycated insulin in plasma of type 2 diabetic subjects using a novel radioimmunoassay. Irish Journal of Medical Science, 170 . p. 10. [Journal article]

Mckillop, Aine, Meade, Angela, Flatt, Peter and O'Harte, Finbarr (2001) Structural characterisation of glycated proinsulin. Irish Journal of Medical Science. Irish Journal of Medical Science, 170 . p. 11. [Journal article]

McKillop, Aine, Mooney, MH, Harriott, P, Flatt, Peter and O'Harte, Finbarr (2001) Evaluation of glycated insulin in diabetic animals using immunocytochemistry and radioimmunoassay. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 286 (3). pp. 524-528. [Journal article]

McKillop, Aine, Mooney, MH, O'Harte, Finbarr and Flatt, Peter (2001) Evaluation of glycated insulin in plasma and biological tissues of diabetic animal models. DIABETOLOGIA, 44 (Suppl. 1). p. 1222. [Journal article]

O'Harte, Finbarr, Mooney, MH, Kelly, CMN, McKillop, Aine and Flatt, Peter (2001) Degradation and glycemic effects of His(7)-glucitol glucagon-like peptide-1(7-36)amide in obese diabetic ob/ob mice. REGULATORY PEPTIDES, 96 (3). pp. 95-104. [Journal article]

Boyd, AC, Abdel-Wahab, Yasser, McKillop, Aine, McNulty, Helene, Barnett, CR, O'Harte, Finbarr and Flatt, Peter (2000) Impaired ability of glycated insulin to regulate plasma glucose and stimulate glucose transport and metabolism in mouse abdominal muscle. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1523 (1). pp. 128-134. [Journal article]

McKillop, Aine, Abdel-Wahab, Yasser and Flatt, Peter (2000) The traditional plant treatment, Sambucus nigra (elder), exhibits insulin-like and insulin-releasing actions in vitro. JOURNAL OF NUTRITION, 130 (1). pp. 15-20. [Journal article]

McKillop, Aine, McCluskey, Janie, Boyd, AC, Mooney, MH, Flatt, Peter and O'Harte, Finbarr (2000) Production and characterization of specific antibodies for evaluation of glycated insulin in plasma and biological tissues. JOURNAL OF ENDOCRINOLOGY, 167 (1). pp. 153-163. [Journal article]

O'Harte, Finbarr, Boyd, AC, McKillop, Aine, Abdel-Wahab, Yasser, McNulty, Helene, Barnett, CR, Conlon, JM, Hojrup, P and Flatt, Peter (2000) Structure, antihyperglycemic activity and cellular actions of a novel diglycated human insulin. PEPTIDES, 21 (10). pp. 1519-1526. [Journal article]

O'Harte, Finbarr, McKillop, Aine, Mooney, MH and Flatt, Peter (2000) Development and use of a specific radioimmunoassay for detection of glycated insulin in diabetes. DIABETOLOGIA, 43 (Suppl. 1). p. 208. [Journal article]

Mckillop, Aine, O'Hare, Mairead, Craig, John and Halliday , Henry (1998) Incidence of molecular forms of human milk bile salt stimulated lipase. Pediatric Research , 43 . pp. 101-104. [Journal article]

This list was generated on Tue Jul 22 08:24:55 2014 BST.