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Jump to: 2010 | 2009 | 2008 | 2007 | 2006 | 2004
Number of items: 14.

2010

Hunter, Kerry, O'Harte, FPM, Abdel-Wahab, YHA and Flatt, PR (2010) Evaluation of the inhibitory action of islet amyloid polypeptide on insulin secretion from clonal rat pancreatic beta-cells. REGULATORY PEPTIDES, 164 (1, Sp. Iss. SI). p. 44. [Journal article]

2009

Irwin, Nigel, Hunter, Kerry, Frizzell, Norma and Flatt, Peter (2009) Antidiabetic effects of sub-chronic activation of the GIP receptor alone and in combination with background exendin-4 therapy in high fat fed mice. REGULATORY PEPTIDES, 153 (1-3). pp. 70-76. [Journal article]

Irwin, Nigel, McClean, Paula, Hunter, Kerry and Flatt, Peter (2009) Metabolic effects of sustained activation of the GLP-1 receptor alone and in combination with background GIP receptor antagonism in high fat-fed mice. DIABETES OBESITY AND METABOLISM, 11 (6). pp. 603-610. [Journal article]

Irwin, Nigel, McClean, Paula, Patterson, Steven, Hunter, Kerry and Flatt, Peter (2009) Active immunisation against gastric inhibitory polypeptide (GIP) improves blood glucose control in an animal model of obesity-diabetes. BIOLOGICAL CHEMISTRY, 390 (1). pp. 75-80. [Journal article]

2008

Irwin, Nigel, Hunter, Kerry and Flatt, Peter (2008) Comparison of independent and combined chronic metabolic effects of GIP and CB1 receptor blockade in high-fat fed mice. PEPTIDES, 29 (6). pp. 1036-1041. [Journal article]

Irwin, Nigel, Hunter, Kerry, Frizzell, Nonna and Flatt, Peter (2008) Antidiabetic effects of sub-chronic administration of the cannabinoid receptor (CB1) antagonist, AM251, in obese diabetic (ob/ob) mice. EUROPEAN JOURNAL OF PHARMACOLOGY, 581 (1-2). pp. 226-233. [Journal article]

McClean, Paula, Irwin, Nigel, Hunter, Kerry, Gault, Victor and Flatt, Peter (2008) (Pro(3)) GIP[mPEG]: novel, long-acting, mPEGylated antagonist of gastric inhibitory polypeptide for obesity-diabetes (diabesity) therapy. BRITISH JOURNAL OF PHARMACOLOGY, 155 (5). pp. 690-701. [Journal article]

2007

Gault, Victor, Hunter, Kerry, Irwin, Nigel, Green, Brian D, Greer, Brett, Harriott, Patrick, O'Harte, Finbarr and Flatt, Peter (2007) Characterisation and biological activity of Glu(3) amino acid substituted GIP receptor antagonists. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 461 (2). pp. 263-274. [Journal article]

Gault, Victor, Hunter, Kerry, Irwin, Nigel, Greer, Brett, Green, Brian D, Harriott, Patrick, O'Harte, Finbarr and Flatt, Peter (2007) Characterisation and glucoregulatory actions of a novel acylated form of the (Pro(3))GIP receptor antagonist in type 2 diabetes. BIOLOGICAL CHEMISTRY, 388 (2). pp. 173-179. [Journal article]

Irwin, Nigel, Hunter, Kerry and Flatt, Peter (2007) Comparison of the metabolic effects of GIP receptor antagonism and PYY(3-36) receptor activation in high fat fed mice. PEPTIDES, 28 (11). pp. 2192-2198. [Journal article]

O'Harte, Finbarr, Hunter, Kerry, Gault, Victor, Irwin, Nigel, Green, Brian D., Greer, Brett, Harriott, Patrick, Bailey, Clifford J. and Flatt, Peter (2007) Antagonistic effects of two novel GIP analogs, (Hyp(3))GIP and (Hyp(3)) GIPLys(16)PAL, on the biological actions of GIP and longer-term effects in diabetic ob/ob mice. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 292 (6). E1674-E1682. [Journal article]

2006

Gault, Victor, Hunter, Kerry, Irwin, Nigel, Green, BD, O'Harte, Finbarr and Flatt, Peter (2006) Characterisation of novel glucose-dependent insulinotropic polypeptide (GIP) antagonists generated through amino acid substitution at position Glu(3). DIABETOLOGIA, 49 (Suppl. 1). 0672. [Journal article]

O'Harte, Finbarr, Hunter, K., Gault, Victor, Irwin, Nigel, Harriott, P. and Flatt, Peter (2006) Cellular and metabolic evaluation of (hydroxyproline(3))-GIP as new stable GIP receptor antagonist with antidiabetic potential. DIABETOLOGIA, 49 (Suppl. 1). 0661. [Journal article]

2004

Hunter, Kerry, Irwin, Nigel, Green, BD, Flatt, Peter, O'Harte, Finbarr and Gault, Victor (2004) Novel long-acting enzyme-resistant glucose-dependent insulinotropic polypeptide receptor agonists with improved antihyperglycaemic and insulinotropic activity. Irish Journal of Medical Science, 173 (S1) . p. 35. [Journal article]

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