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Monitoring genotoxicity during the photocatalytic degradation ofp-nitrophenol

Biomedical Sciences Research Institute Computer Science Research Institute Environmental Sciences Research Institute Nanotechnology & Advanced Materials Research Institute

Sekler, MS, Levi, Y, Polyak, B, Novoa, A, Dunlop, PSM, Byrne, JA and Marks, RS (2004) Monitoring genotoxicity during the photocatalytic degradation ofp-nitrophenol. Journal of Applied Toxicology, 24 (5). p. 395. [Journal article]

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URL: http://dx.doi.org/10.1002/jat.1029

DOI: doi:10.1002/jat.1029

Abstract

p-Nitrophenol is a common structural unit of many pesticides and was chosen as a model compound to monitor genotoxicity during photocatalytic degradation. The genotoxicity of p-nitrophenol (PNP) and its breakdown products was measured using a bioluminescent bacterial bioassay, Vitotox(TM). The genotoxic potential decreased with the concomitant photocatalytic degradation of the parent PNP concentration. The rate of genotoxicity reduction was slower than the rate of removal of the parent PNP, due to the formation of genotoxic by-products. After 6 h of photocatalytic treatment the total genotoxicity was removed. These results indicate that bioassays can be used as a simple and highly sensitive method for monitoring the general toxicity of chemical pollutants before, during and after photocatalytic treatment or other destructive processes.

Item Type:Journal article
Faculties and Schools:Faculty of Computing & Engineering
Faculty of Computing & Engineering > School of Engineering
Research Institutes and Groups:Engineering Research Institute
Engineering Research Institute > Nanotechnology & Integrated BioEngineering Centre (NIBEC)
ID Code:7478
Deposited By:Dr Patrick Dunlop
Deposited On:18 Jan 2010 12:40
Last Modified:18 Aug 2011 11:16

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