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Do hydroxy-carotenoids prevent coronary heart disease? A comparison between Belfast and Toulouse

Biomedical Sciences Research Institute Computer Science Research Institute Environmental Sciences Research Institute Nanotechnology & Advanced Materials Research Institute

Howard, AN, Williams, NR, Palmer, CR, Cambou, JP, Evans, AE, Foote, JW, MarquesVidal, P, McCrum, EE, Ruidavets, JB, Nigdikar, SV, RajputWilliams, J and Thurnham, DI (1996) Do hydroxy-carotenoids prevent coronary heart disease? A comparison between Belfast and Toulouse. INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH, 66 (2). pp. 113-118. [Journal article]

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High intakes of antioxidants in fruit, vegetables and wine are thought to protect against coronary heart disease (CHD). Because people in Toulouse have a much lower incidence of CHD compared with Belfast, the plasma concentrations of antioxidant vitamins and carotenoids in the two populations have been compared. The major difference was in some of the plasma carotenoids. Hydroxy-carotenoids were twice as high in Toulouse in both sexes, notably lutein which occurs principally in dark green vegetables and beta-cryptoxanthin which occurs chiefly in citrus fruits. In addition, alpha-carotene was 50% higher in Toulouse, gamma-tocopherol was 50% higher in Belfast. Other plasma vitamins and carotenoids were nor significantly different. If antioxidants play a role in preventing CHD, then the hydroxy-carotenoids are major candidates for further investigation.

Item Type:Journal article
Faculties and Schools:Faculty of Life and Health Sciences
Research Institutes and Groups:Institute of Nursing and Health Research
Institute of Nursing and Health Research > Maternal, Fetal and Infant Research
ID Code:7398
Deposited By:Ms Evie Gardner
Deposited On:27 Jan 2010 15:47
Last Modified:04 Aug 2011 15:32

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