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Screening and recruitment procedure of late-middle aged and older subjects: the ZENITH study

Biomedical Sciences Research Institute Computer Science Research Institute Environmental Sciences Research Institute Nanotechnology & Advanced Materials Research Institute

Polito, A, Meunier, N, Andriollo-Sanchez, M, Catasta, G, Azzini, E, Simpson, EEA, O'Connor, JM, Roussel, AM, Ferry, M, Coudray, C and Maiani, G (2005) Screening and recruitment procedure of late-middle aged and older subjects: the ZENITH study. EUROPEAN JOURNAL OF CLINICAL NUTRITION, 59 (Suppl. 2). S8-S12. [Journal article]

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DOI: 10.1038/sj.ejcn.1602287

Abstract

Objective: To report the rational, design, recruitment, baseline characteristics and preliminary overview of volunteers in the ZENITH study. Design: A multicentre prospective intervention study employing a randomised double-blind design. Setting: Clermont-Ferrand, Theix (France), Coleraine (Northern Ireland), Grenoble (France), Rome (Italy). Participants: Healthy men and women middle-aged (55-70 y) and older volunteers (70-87 y). Interventions: At baseline (prior to zinc (Zn) supplementation), all volunteers underwent a full clinical examination, anthropometric measurements, health and lifestyle questionnaire, Mini Mental State Examination, Geriatric Depression Scale, and biochemistry profile. Results: In total, 842 volunteers (378 men and 464 women) were invited to take part in the study. A total of 49% of these volunteers were excluded on the basis of inclusion/exclusion criteria. In total, 433 participants were admitted to the Zn supplementation for 6 months. During this period, about 10% of volunteers dropped out from the study. Conclusions: A total of 387 subjects (1197 male and 190 female subjects) successfully completed the supplementation phase of the ZENITH study.

Item Type:Journal article
Faculties and Schools:Faculty of Life and Health Sciences
Faculty of Life and Health Sciences > School of Biomedical Sciences
Faculty of Life and Health Sciences > School of Psychology
Research Institutes and Groups:Biomedical Sciences Research Institute
Psychology Research Institute
Biomedical Sciences Research Institute > Northern Ireland Centre for Food and Health (NICHE)
Psychology Research Institute > Health and Wellbeing
ID Code:7178
Deposited By:Professor Jacqueline McCormack
Deposited On:18 Jan 2010 11:32
Last Modified:15 Dec 2011 16:03

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