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Image registration and subtraction for the visualization of change in diabetic retinopathy screening

Biomedical Sciences Research Institute Computer Science Research Institute Environmental Sciences Research Institute Nanotechnology & Advanced Materials Research Institute

McRitchie, Ian N., Hart, Patricia M. and Winder, John (2006) Image registration and subtraction for the visualization of change in diabetic retinopathy screening. COMPUTERIZED MEDICAL IMAGING AND GRAPHICS, 30 (3). pp. 139-145. [Journal article]

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DOI: 10.1016/j.compmedimag.2006.01.002

Abstract

Diabetic retinopathy (DR) is a leading cause of blindness in people of working age in developed countries. DR is characterized by lesions of the retinal microvasculature. This paper describes a technique for visualizing the changes which occur in retinal pathology over a 1 year interval. Pairs of retinal images of the same eye were acuired 12 months apart within a DR screening programme. The images were normalized, registered and subtracted to generate a contrast-enhanced difference image displaying changes in retinal appearance. The normalization factor and registration error were quantified for 104 pairs of retinal images. (c) 2006 Elsevier Ltd. All rights reserved.

Item Type:Journal article
Keywords:registration; subtraction; detection; visualization; retinopathy
Faculties and Schools:Faculty of Life and Health Sciences
Faculty of Life and Health Sciences > School of Health Sciences
Research Institutes and Groups:Institute of Nursing and Health Research > Centre for Health and Rehabilitation Technologies
ID Code:6452
Deposited By:Dr John Winder
Deposited On:27 Jan 2010 16:20
Last Modified:29 Feb 2012 10:51

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