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The effect of acute aerobic exercise on pulse wave velocity and oxidative stress following postprandial hypertriglyceridemia in healthy men

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McClean, Conor, McLaughlin, JAD, Burke, GA, Murphy, Marie, Trinick, Tom, Duly, Ellie and Davison, Gareth (2007) The effect of acute aerobic exercise on pulse wave velocity and oxidative stress following postprandial hypertriglyceridemia in healthy men. European Journal of Applied Physiology, 100 . pp. 225-234. [Journal article]

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DOI: 10.1007/s00421-007-0422-y

Abstract

Oxidative stress is postulated to be responsible for the postprandial impairments in vascular function. The purpose of this study was to measure pulse wave velocity (PWV) and markers of postprandial oxidative stress before and after an acute bout of moderate exercise. Ten trained male subjects (age 21.5 ± 2.5 years, VO2 max 58.5 ±7.1 ml kg–1 min–1) participated in a randomised crossover design: (1) high-fat meal alone (2) high-fat meal followed 2 h later by a bout of 1 h moderate (60% max HR) exercise.PWV was examined at baseline, 1, 2, 3, and 4 h postprandially. Blood Lipid hydroperoxides (LOOHs), Superoxide dismutase (SOD) and other biochemicalmarkers were measured. PWV increased at 1 h (6.49 ± 2.1 m s–1), 2 h (6.94 ± 2.4 m s–1), 3 h (7.25 ± 2.1 m s–1) and 4 h (7.41 ± 2.5 m s–1) respectively, in the control trial(P < 0.05). There was no change in PWV at 3 h (5.36 ± 1.1 m s–1) or 4 h (5.95 ± 2.3 m s–1) post ingestion in the exercise trial (P > 0.05). LOOH levels decreased at 3 hpost ingestion in the exercise trial compared to levels at 3 h (P < 0.05) in the control trial. SOD levels were lower at 3 h post ingestion in the control trial compared to 3 h in theexercise trial (0.52 ± 0.05 vs. 0.41 ± 0.1 units ll–1; P < 0.05). These findings suggest that a single session of aerobic exercise can ameliorate the postprandial impairmentsin arterial function by possibly reducing oxidative stress levels.

Item Type:Journal article
Keywords:Exercise, Postprandial lipaemia, Oxidative stress,Vascular function, Lipid hydroperoxides
Faculties and Schools:Faculty of Computing & Engineering
Faculty of Life and Health Sciences
Faculty of Life and Health Sciences > Ulster Sports Academy
Research Institutes and Groups:Sport and Exercise Sciences Research Institute
Sport and Exercise Sciences Research Institute > Centre for Physical Activity and Health
ID Code:6095
Deposited By:Dr Conor McClean
Deposited On:13 Feb 2010 19:02
Last Modified:28 Jun 2011 16:03

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