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Solid-state fermentation: a promising microbial technology for secondary metabolite production

Biomedical Sciences Research Institute Computer Science Research Institute Environmental Sciences Research Institute Nanotechnology & Advanced Materials Research Institute

Robinson, T, Singh, D and Singh - Nee Nigam, Poonam (2001) Solid-state fermentation: a promising microbial technology for secondary metabolite production. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 55 (3). pp. 284-289. [Journal article]

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Abstract

Solid state (substrate) fermentation (SSF) has been used successfully for the production of enzymes and secondary metabolites. These products are associated with the stationary phase of microbial growth and are produced on an industrial scale for use in agriculture and the treatment of disease, Many of these secondary metabolites are still produced by submerged liquid fermentations (SmF) even though production by this method has been shown to be less efficient than SSF As large-scale production increases further, so do the costs and energy demands. SSF has been shown to produce a more stable product, requiring less energy, in smaller fermenters, with easier downstream processing measures. In this article we review an important area of biotechnology, since the recent evidence indicates that bacteria and fungi, growing under SSF conditions, are more than capable of supplying the growing global demand for secondary metabolites.

Item Type:Journal article
Faculties and Schools:Faculty of Life and Health Sciences
Faculty of Life and Health Sciences > School of Biomedical Sciences
Research Institutes and Groups:Biomedical Sciences Research Institute
Biomedical Sciences Research Institute > Infection and Immunity/Microbiology
ID Code:5494
Deposited By:Dr Poonam Singh - Nee Nigam
Deposited On:21 Dec 2009 10:54
Last Modified:04 Aug 2011 09:48

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