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Comparative bioactivity studies on two Mimosa species

Biomedical Sciences Research Institute Computer Science Research Institute Environmental Sciences Research Institute Nanotechnology & Advanced Materials Research Institute

Genest, Samuel, Kerr, Conor, Shah, Ankit, Rahman, M. Mukhlesur, Saif-E-Naser, Gadria M. M., Singh - Nee Nigam, Poonam, Nahar, Lutfun and Sarker, Satyajit D. (2008) Comparative bioactivity studies on two Mimosa species. BOLETIN LATINOAMERICANO Y DEL CARIBE DE PLANTAS MEDICINALES Y AROMATICAS, 7 (1). pp. 38-43. [Journal article]

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Abstract

Comparative antioxidant, antibacterial activities and general toxicity studies on the n-hexane, dichloromethane (DCM) and methanol (MeOH) extracts of Mimosa pudica and Mimosa rubicaulis, two Bangladeshi medicinal plants, were carried out, using the 2,2-diphenyl-1-picryl-hydrazyl (DPPH) assay, the resazurin microtitre plate based assay, and the brine shrimp lethality assay, respectively. The DCM and MeOH extracts of both M. pudica and M. rubicaulis showed prominent antioxidant property, with the RC50 values ranging from 4.70 x 10(-1) to 2.10 x 10(-2) mg/mL. While M. rubicaulis did not show any antibacterial activity, the DCM and the MeOH extracts of M. pudica displayed considerable bacteriostatic activity against all six bacterial strains (MIC range = 0.625-2.50 mg/mL) including Bacillus cereus, B. subtilis, Escherichia coli, ampicillin-resistant Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa. None of these plants exhibited any significant toxicity towards brine shrimps.

Item Type:Journal article
Faculties and Schools:Faculty of Life and Health Sciences
Faculty of Life and Health Sciences > School of Biomedical Sciences
Research Institutes and Groups:Biomedical Sciences Research Institute
Biomedical Sciences Research Institute > Infection and Immunity/Microbiology
ID Code:5454
Deposited By:Dr Poonam Singh - Nee Nigam
Deposited On:21 Dec 2009 10:12
Last Modified:04 Aug 2011 09:48

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