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Acute post-ingestion changes in plasma ascorbic acid concentration: Relationship to dose and to existing body stores.

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Benzie, IFF and Strain, JJ (1997) Acute post-ingestion changes in plasma ascorbic acid concentration: Relationship to dose and to existing body stores. NUTRITION RESEARCH, 17 (2). pp. 187-190. [Journal article]

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Abstract

Plasma ascorbic acid concentrations were measured in 27 adults before and after ingestion of 0.5 - 3.0 g of vitamin C. Mean (SEM) fasting concentration was 64 (3) mu mol/l, with no significant male-female difference. There was a significant correlation between the response and log dose (r = 0.928; P <0.01). There was no significant correlation (r = 0.14; P >0.1) between the dose-corrected increase and the fasting concentration; 0.5 g caused a greater increase than 0.25 g (mean increases 56 and 33 mu mol/l respectively; P <0.01); doses of 1.0 g and 2.0 g did not cause significantly greater responses. Results indicate that i) response to ingestion of vitamin C is dose dependent and independent of body stores of the vitamin, ii) a 0.5g dose appears optimal in terms of increasing the plasma ascorbic acid concentration. Copyright (C) 1997 Elsevier Science Inc.

Item Type:Journal article
Faculties and Schools:Faculty of Life and Health Sciences
Faculty of Life and Health Sciences > School of Biomedical Sciences
Research Institutes and Groups:Biomedical Sciences Research Institute
Biomedical Sciences Research Institute > Northern Ireland Centre for Food and Health (NICHE)
ID Code:5273
Deposited By:Mrs Alison Deehan
Deposited On:14 Jan 2010 15:01
Last Modified:30 Jun 2011 15:50

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