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Elucidation of trends within venom components from the snake families Elapidae and Viperidae using gel filtration chromatography

Biomedical Sciences Research Institute Computer Science Research Institute Environmental Sciences Research Institute Nanotechnology & Advanced Materials Research Institute

Graham, Robert Leslie James, Graham, C, Theakston, David, McMullan, Geoffrey and Shaw, Chris (2008) Elucidation of trends within venom components from the snake families Elapidae and Viperidae using gel filtration chromatography. TOXICON, 51 (1). pp. 121-129. [Journal article]

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DOI: 10.1016/j.toxicon.2007.08.010

Abstract

Research into snake venom components has intensified over the last number of decades, particularly that work directed towards the discovery of novel agents with potential applications in clinical therapy. In the present study we report, for the first time, defined patterns observed in the G-50 chromatographic elution profiles from 30 snake venoms taken from Elapidae and Viperidae families, as well as previously unreported patterns within subfamilies of these snake species. Development of this chromatographic technique thus offers a rapid method for the general classification of snakes within these families as well as providing insights into hitherto uncharacterised trends within the venoms of snake subfamilies that have opened new avenues for further investigation. (C) 2007 Elsevier Ltd. All rights reserved.

Item Type:Journal article
Faculties and Schools:Faculty of Life and Health Sciences
Faculty of Life and Health Sciences > School of Biomedical Sciences
Research Institutes and Groups:Biomedical Sciences Research Institute
Biomedical Sciences Research Institute > Northern Ireland Centre for Food and Health (NICHE)
ID Code:5010
Deposited By:Professor Geoffrey McMullan
Deposited On:05 Jan 2010 15:50
Last Modified:16 May 2012 15:30

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