Abstract

Single-cell protein (SCP) produced from a novel thermotolerant methylotrophic Bacillus sp. KISRI-TM IA was fed to groups of 10 male and 10 female Wistar rats at levels of 0, 10, 20, and 30 percent of total diets. The feeding of KISRI-TM lA did not adversely affect growth, feed intake or hematological values of rats. Water intake of male rats decreased with increasing level of SCP in the diet. Urinary pH showed dose-dependent reductions in both sexes. Plasma alkaline phosphatase and alanine aminotransferase were significantly (P < .05) reduced by increasing levels of dietary SCF. However, no significant (p > .05) abnormalities were observed in the weights or histopathological appearances of the organs. It was concluded that the KISRI-TM lA SCP could serve as a potential dietary ingredient at levels of up to 30% for poultry, young lambs and calves.