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Electro-sensitisation of mammalian cells and tissues to ultrasound: a novel tumour treatment modality

Biomedical Sciences Research Institute Computer Science Research Institute Environmental Sciences Research Institute Nanotechnology & Advanced Materials Research Institute

Haro, AMR, Smyth, A, Hughes, P, Reid, CN and McHale, Anthony (2005) Electro-sensitisation of mammalian cells and tissues to ultrasound: a novel tumour treatment modality. CANCER LETTERS, 222 (1). pp. 49-55. [Journal article]

Full text not available from this repository.

DOI: 10.1016/j.canlet.2004.09.033

Abstract

This study demonstrates that mammalian cell targets (erythrocytes and tumour cells) may be sensitised to ultrasound using electric pulses and this combination treatment results in destruction of those cells in vitro. It further demonstrates that when a tumour mass is treated in vivo using combined electric field and ultrasound therapy, significant retardation of tumour growth has been observed using a mouse tumour model. We suggest that combined electric field and ultrasound (CEFUS) therapy may provide a novel, drug-free treatment modality for cancer. (c) 2004, Elsevier Ireland Ltd. All rights reserved.

Item Type:Journal article
Faculties and Schools:Faculty of Life and Health Sciences
Faculty of Life and Health Sciences > School of Pharmacy and Pharmaceutical Science
Research Institutes and Groups:Biomedical Sciences Research Institute
Biomedical Sciences Research Institute > Pharmaceutical Science and Practice
ID Code:3986
Deposited By:Professor Anthony McHale
Deposited On:18 Dec 2009 11:41
Last Modified:04 Dec 2012 11:25

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