Haro, AMR, Smyth, A, Hughes, P, Reid, CN and McHale, Anthony (2005) Electro-sensitisation of mammalian cells and tissues to ultrasound: a novel tumour treatment modality. CANCER LETTERS, 222 (1). pp. 49-55. [Journal article]
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This study demonstrates that mammalian cell targets (erythrocytes and tumour cells) may be sensitised to ultrasound using electric pulses and this combination treatment results in destruction of those cells in vitro. It further demonstrates that when a tumour mass is treated in vivo using combined electric field and ultrasound therapy, significant retardation of tumour growth has been observed using a mouse tumour model. We suggest that combined electric field and ultrasound (CEFUS) therapy may provide a novel, drug-free treatment modality for cancer. (c) 2004, Elsevier Ireland Ltd. All rights reserved.
|Item Type:||Journal article|
|Faculties and Schools:||Faculty of Life and Health Sciences|
Faculty of Life and Health Sciences > School of Pharmacy and Pharmaceutical Science
|Research Institutes and Groups:||Biomedical Sciences Research Institute|
Biomedical Sciences Research Institute > Pharmaceutical Science and Practice
|Deposited By:||Professor Anthony McHale|
|Deposited On:||18 Dec 2009 11:41|
|Last Modified:||04 Dec 2012 11:25|
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