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Electro-biosorptive accumulation for use in enhanced detection of fluorogenic tracers and the removal of toxic entities from dilute solutions

Biomedical Sciences Research Institute Computer Science Research Institute Environmental Sciences Research Institute Nanotechnology & Advanced Materials Research Institute

Nomikou, Nikolitsa and McHale, Anthony (2007) Electro-biosorptive accumulation for use in enhanced detection of fluorogenic tracers and the removal of toxic entities from dilute solutions. BIOTECHNOLOGY LETTERS, 29 (4). pp. 561-567. [Journal article]

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DOI: 10.1007/s10529-006-9286-1

Abstract

An accumulating process based on electric field-assisted biosorption is described to facilitate the accumulation and enhanced detection of organic fluorogenic marker species in aqueous solution. Fluorescein was detected at concentrations as low as 0.6 mu g l(-1). Using a mammalian cell-based bioassay, we demonstrate the use of the system to remove the toxic effects of species such as ethidium bromide and doxorubicin from complex solutions such as tissue culture medium. The use of such a system for the detection and removal of trace contaminants is discussed.

Item Type:Journal article
Faculties and Schools:Faculty of Life and Health Sciences
Faculty of Life and Health Sciences > School of Pharmacy and Pharmaceutical Science
Research Institutes and Groups:Biomedical Sciences Research Institute
Biomedical Sciences Research Institute > Pharmaceutical Science and Practice
ID Code:3983
Deposited By:Professor Anthony McHale
Deposited On:18 Dec 2009 14:26
Last Modified:04 Dec 2012 11:23

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