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The effect of simulated lens yellowing and opacification on blue-on-yellow acuity and contrast sensitivity

Biomedical Sciences Research Institute Computer Science Research Institute Environmental Sciences Research Institute Nanotechnology & Advanced Materials Research Institute

Zlatkova, Margarita, Coulter, EE and Anderson, Roger (2006) The effect of simulated lens yellowing and opacification on blue-on-yellow acuity and contrast sensitivity. VISION RESEARCH, 46 (15). pp. 2432-2442. [Journal article]

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DOI: 10.1016/j.visres.2006.01.025

Abstract

Short-wavelength-sensitive (SWS) resolution acuity has been reported to be limited by the density of the responding ganglion cells for people without appreciable age-related lenticular change. This study measured the robustness of SWS-cone acuity and contrast sensitivity (CS) to simulated lens yellowing and opacification. Resolution acuity at 8 deg eccentricity proved robust to significant amounts of yellowing and remained lower than detection acuity, indicating that the resolution continued to be limited by ganglion cell density. Both the detection and resolution CS functions were affected by simulated lens yellowing, except for resolution close to the CS cut-off. For simulated opacification, only dense opacity significantly affected performance. SWS resolution acuity and CS close to the resolution limit are resistant to moderate simulated age-related lens changes and continue to be mediated by the density of the responding ganglion cells, indicating important clinical potential to measure SWS neural losses of vision in older subjects. (c) 2006 Elsevier Ltd. All rights reserved.

Item Type:Journal article
Faculties and Schools:Faculty of Life and Health Sciences
Faculty of Life and Health Sciences > School of Biomedical Sciences
Research Institutes and Groups:Biomedical Sciences Research Institute
Biomedical Sciences Research Institute > Vision
ID Code:3932
Deposited By:Dr Margarita Vidinova
Deposited On:09 Feb 2010 10:14
Last Modified:04 Aug 2011 09:51

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