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Iminodiacetate and nitrilotriacetate degradation by Kluyveromyces marxianus IMB3

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Ternan, Nigel and McMullan, Geoffrey (2002) Iminodiacetate and nitrilotriacetate degradation by Kluyveromyces marxianus IMB3. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 290 (2). pp. 802-805. [Journal article]

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DOI: 10.1006/bbrc.2001.6233

Abstract

The thermotolerant yeast Kluyveromyces marxianus IMB3 was capable of utilising either iminodiacetate or nitrilotriacetate as a sole source of nitrogen for growth. Cell extracts contained iminodiacetate dehydrogenase and nitrilotriacetate monooxygenase activities, suggesting the presence in the yeast of orthologues of these bacterial enzymes. The activities were not detectable in complete medium-growth cells, nor in nitrogen-starved cells, suggesting an inducible biodedgradation pathway for biodegradation of these xenobiotics, which has not been previously reported in a eukaryotic cell system. This observation emphasises the hitherto unrealised importance of yeast strains in the biodegradation of xenobiotics in the environment. (C) 2002 Elsevier Science.

Item Type:Journal article
Faculties and Schools:Faculty of Life and Health Sciences
Faculty of Life and Health Sciences > School of Biomedical Sciences
Research Institutes and Groups:Biomedical Sciences Research Institute
Biomedical Sciences Research Institute > Northern Ireland Centre for Food and Health (NICHE)
ID Code:3685
Deposited By:Dr Nigel Ternan
Deposited On:17 Dec 2009 14:12
Last Modified:16 May 2012 15:12

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