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Vitamin D status and its determinants in adolescents from the Northern Ireland Young Hearts 2000 cohort

Biomedical Sciences Research Institute Computer Science Research Institute Environmental Sciences Research Institute Nanotechnology & Advanced Materials Research Institute

Hill, Tom R., Cotter, Alice A., Mitchell, Sarah, Boreham, Colin A., Dubitzky, W, Murray, Liam, Strain, JJ, Flynn, Albert, Robson, Paula J., Wallace, Julie, Kiely, Mairead and Cashman, Kevin D. (2008) Vitamin D status and its determinants in adolescents from the Northern Ireland Young Hearts 2000 cohort. BRITISH JOURNAL OF NUTRITION, 99 (5). pp. 1061-1067. [Journal article]

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DOI: 10.1017/S0007114507842826

Abstract

Despite recent concerns about the high prevalence of sub-clinical vitamin D deficiency in adolescents, relatively few studies have investigated the underlying reasons. The objective of the present study was to investigate the prevalence and predictors of vitamin D inadequacy among a large representative sample of adolescents living in Northern Ireland (54-55 degrees N). Serum concentrations of 25-hydroxyvitamin D (25(OH)D) were analysed by enzyme-immunoassay in a subgroup of 1015 of the Northern Ireland Young Hearts 2000 cohort; a cross-sectional study of 12 and 15 year-old boys and girls. Overall mean 25(OH)D concentration throughout the year was 64.3 (range 5-174) nmol/l; 56.7 and 78.1 nmol/l during winter and summer, respectively. Reported intakes of vitamin D were very low (median 1.7 mu g/d). Of those adolescents studied, 3 % and 36 % were vitamin D deficient and inadequate respectively, as defined by serum 25(OH)D concentrations < 25 and < 50 nmol/l. Of the subjects, 46 % and 17 % had vitamin D inadequacy during winter and summer respectively. Gender differences were also evident with 38 % and 55 % of boys and girls respectively classified as vitamin D inadequate during winter (P < 0.001). Predictors of vitamin D inadequacy during winter were vitamin D intake and gender. In conclusion, there is a high prevalence of vitamin D inadequacy in white-skinned adolescents in Northern Ireland, particularly during wintertime and most evident in girls. There is a clear need for dietary recommendations for vitamin D in this age group and for creative strategies to increase overall vitamin D status in the population.

Item Type:Journal article
Faculties and Schools:Faculty of Life and Health Sciences
Faculty of Life and Health Sciences > School of Biomedical Sciences
Research Institutes and Groups:Biomedical Sciences Research Institute
Biomedical Sciences Research Institute > Northern Ireland Centre for Food and Health (NICHE)
ID Code:3561
Deposited By:Dr Julie Wallace
Deposited On:15 Dec 2009 14:55
Last Modified:11 Feb 2013 15:47

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