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Effects of an Integrated medicines management program on medication appropriateness in hospitalized patients

Biomedical Sciences Research Institute Computer Science Research Institute Environmental Sciences Research Institute Nanotechnology & Advanced Materials Research Institute

Burnett, Kathryn, Scott, Michael, Fleming, Glenda, Clark, Christine and McElnay, James (2009) Effects of an Integrated medicines management program on medication appropriateness in hospitalized patients. American Journal of Health-System Pharmacy, 66 (May 1). pp. 854-859. [Journal article]

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Purpose. The effects of an integrated medicines management (IMM) program on medication appropriateness are discussed.Methods. Patients enrolled in an IMM project within a hospital were randomly allocated to either a control or an intervention group. Patients in the control group received standard pharmaceutical care, while the intervention patients received the IMM service. The appropriateness of the medications prescribed was estimated on admission and discharge using the Medicines Appropriateness Index (MAI), which ranged from 0 (no prescribing problems) to 18 (most prescribing problems). For each medication scored, the difference between admission and discharge MAI scores for individual patients was calculated.Results. Scoring was completed on 1711 medications prescribed for 117 patients.There was a statistically significant difference (p = 0.03) in the mean MAI scores ondischarge between the intervention and control groups (5.69 versus 9.97, respectively).There was also a statistically significant difference (p = 0.00003) in the meanMAI scores on admission and discharge (17.48 versus 5.69, respectively) for theintervention group. The intervention group had a mean ± S.D. difference of –11.78 ±14.64, while the control group had a mean ± S.D. difference of –3.19 ± 11.80. The differencewas statistically significant (p = 0.0011) between the two groups.Conclusion. This study demonstrated significant improvements in the appropriatenessof medications on discharge for patients receiving an IMM service compared with patients who did not receive this service.

Item Type:Journal article
Keywords:Drug use, Hospitals, Interventions, Pharmaceutical Services, Prescribing
Faculties and Schools:Faculty of Life and Health Sciences
Faculty of Life and Health Sciences > School of Pharmacy and Pharmaceutical Science
Research Institutes and Groups:Biomedical Sciences Research Institute
Biomedical Sciences Research Institute > Pharmaceutical Science and Practice
ID Code:3373
Deposited By:Dr Kathryn Burnett
Deposited On:15 Dec 2009 09:57
Last Modified:19 Nov 2012 14:51

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