Nomikou, Nikolitsa, Fowley, Colin, Byrne, Niall M., McCaughan, Bridgeen, MCHALE, AP and Callan, John F. (2012) Microbubble-sonosensitiser conjugates as therapeutics in sonodynamic therapy. CHEMICAL COMMUNICATIONS, 48 (67). pp. 8332-8334. [Journal article]
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DOI: 10.1039/c2cc33913g
Abstract
A Rose Bengal sonosensitiser has been covalently attached to a lipid microbubble and the resulting conjugate shown to produce higher levels of singlet oxygen, enhanced cytotoxicity in a cancer cell line and a greater reduction in tumour growth than the sonosensitiser alone.
| Item Type: | Journal article |
|---|---|
| Faculties and Schools: | Faculty of Life and Health Sciences Faculty of Life and Health Sciences > School of Pharmacy and Pharmaceutical Science |
| Research Institutes and Groups: | Biomedical Sciences Research Institute Biomedical Sciences Research Institute > Pharmaceutical Science and Practice |
| ID Code: | 23453 |
| Deposited By: | Professor John Callan |
| Deposited On: | 27 Sep 2012 13:32 |
| Last Modified: | 19 Nov 2012 15:14 |
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