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Microbubble-sonosensitiser conjugates as therapeutics in sonodynamic therapy

Biomedical Sciences Research Institute Computer Science Research Institute Environmental Sciences Research Institute Nanotechnology & Advanced Materials Research Institute

Nomikou, Nikolitsa, Fowley, Colin, Byrne, Niall M., McCaughan, Bridgeen, MCHALE, AP and Callan, John F. (2012) Microbubble-sonosensitiser conjugates as therapeutics in sonodynamic therapy. CHEMICAL COMMUNICATIONS, 48 (67). pp. 8332-8334. [Journal article]

Full text not available from this repository.

DOI: 10.1039/c2cc33913g

Abstract

A Rose Bengal sonosensitiser has been covalently attached to a lipid microbubble and the resulting conjugate shown to produce higher levels of singlet oxygen, enhanced cytotoxicity in a cancer cell line and a greater reduction in tumour growth than the sonosensitiser alone.

Item Type:Journal article
Faculties and Schools:Faculty of Life and Health Sciences
Faculty of Life and Health Sciences > School of Pharmacy and Pharmaceutical Science
Research Institutes and Groups:Biomedical Sciences Research Institute
Biomedical Sciences Research Institute > Pharmaceutical Science and Practice
ID Code:23453
Deposited By:Professor John Callan
Deposited On:27 Sep 2012 13:32
Last Modified:13 May 2014 14:22

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