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Measurements of immune responses for establishing correlates of vaccine protection against HIV

Biomedical Sciences Research Institute Computer Science Research Institute Environmental Sciences Research Institute Nanotechnology & Advanced Materials Research Institute

Burgers, WA, Manrique, A, Masopust, D, McKinnon, LR, Reynolds, MR, Rolland, M, Blish, C, Chege, GK, Curran, Rhonda M, Fischer , W, Herrera, C and Sather, N (2012) Measurements of immune responses for establishing correlates of vaccine protection against HIV. AIDS Research and Human Retroviruses, 28 (7). pp. 641-648. [Journal article]

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URL: http://online.liebertpub.com/doi/pdf/10.1089/aid.2011.0239

DOI: 10.1089/aid.2011.0239

Abstract

Well-defined correlates of protective immunity are an essential component of rational vaccine development. Despite years of basic science and three HIV vaccine efficacy trials, correlates of immunological protection from HIV infection remain undefined. In December 2010, a meeting of scientists engaged in basic and translational work toward developing HIV-1 vaccines was convened. The goal of this meeting was to discuss current opportunities and optimal approaches for defining correlates of protection, both for ongoing and future HIV-1 vaccine candidates; specific efforts were made to engage young scientists. We discuss here the highlights from the meeting regarding the progress made and the way forward for a protective HIV-1 vaccine.

Item Type:Journal article
Faculties and Schools:Faculty of Life and Health Sciences
Faculty of Life and Health Sciences > School of Nursing
Research Institutes and Groups:Institute of Nursing and Health Research
Institute of Nursing and Health Research > Maternal, Fetal and Infant Research
ID Code:23184
Deposited By:Dr Rhonda Curran
Deposited On:28 Aug 2012 15:06
Last Modified:28 Aug 2012 15:06

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