Ulster University Logo

Ulster Institutional Repository

Laser treated carbon composites for the determination of suicide biomarkers: Development of a forensic diagnosis device

Biomedical Sciences Research Institute Computer Science Research Institute Environmental Sciences Research Institute Nanotechnology & Advanced Materials Research Institute

Marti Villalba, Maria, Slater, Stacey and Davis, James (2009) Laser treated carbon composites for the determination of suicide biomarkers: Development of a forensic diagnosis device. ECS Transactions, 19 . pp. 49-60. [Journal article]

Full text not available from this repository.

Abstract

The ongoing debate about the possible link between the serotonin metabolite - 5-hydroxyindoleacetic acid (5-HIAA) - and suicidal behavior requires a more robust specification of reference ranges for normal and "at risk" subjects. As such, there is a need for a revision of analytical techniques for the speedy, selective and sensitive detection of the monoamine biomarkers. A new approach to the production of a carbon composite electrode and its solvent free, laser ablative modification to enhance the performance in the detection of the neurotransmitters is presented. The integration of the electrodes within conventional chromatographic architectures is assessed and its use in the quantification of 5-HIAA within human urine has been critically evaluated and found to be superior to the HPLC-UV.

Item Type:Journal article
Faculties and Schools:Faculty of Computing & Engineering
Faculty of Computing & Engineering > School of Engineering
Research Institutes and Groups:Engineering Research Institute
Engineering Research Institute > Nanotechnology & Integrated BioEngineering Centre (NIBEC)
ID Code:22440
Deposited By:Professor James Davis
Deposited On:08 Jun 2012 09:26
Last Modified:08 Jun 2012 09:26

Repository Staff Only: item control page