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Prevalence of carriage of antimicrobial resistant strains of Streptococcus pneumoniae in primary school children in Hong Kong

Biomedical Sciences Research Institute Computer Science Research Institute Environmental Sciences Research Institute Nanotechnology & Advanced Materials Research Institute

Boost, MV, O'Donoghue, MM and Dooley, JSG (2001) Prevalence of carriage of antimicrobial resistant strains of Streptococcus pneumoniae in primary school children in Hong Kong. EPIDEMIOLOGY AND INFECTION, 127 (1). pp. 49-55. [Journal article]

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Abstract

A cross-sectional survey was conducted to determine prevalence and assess risk factors for carriage of antibiotic resistant strains of Streptococcus pneumoniae in healthy school children in Hong Kong. Throat swabs were collected from 1455 subjects and written questionnaires providing demographic data and medical history were completed by parents. The overall carriage rate of Streptococcus pneumoniae was 3.5 %, of which 49 % were penicillin resistant. High levels of resistance to tetracycline (73 %), erythromycin (52 %), trimethoprim. (66 %) and ciprofloxacin (57 %) were observed. Carriage was associated with presence of a younger sibling (OR = 1.79) and use of antibiotics (OR = 2.31). High use of day care and small size of housing units did not result in a high rate of carriage. The low rate of carriage may be linked to high use of antibiotics, geographical factors or ethnicity. High rates of antibiotic resistance reflect heavy use of antibiotics by general practitioners.

Item Type:Journal article
Faculties and Schools:Faculty of Life and Health Sciences
Faculty of Life and Health Sciences > School of Biomedical Sciences
Research Institutes and Groups:Biomedical Sciences Research Institute
Biomedical Sciences Research Institute > Northern Ireland Centre for Food and Health (NICHE)
ID Code:22234
Deposited By:Professor James Dooley
Deposited On:15 May 2012 11:53
Last Modified:17 May 2012 14:19

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