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Bell, Partrick, Cuthbertson, Joy, Patterson, Steven and O'Harte, Finbarr (2011) Additive hypoglycaemic effect of nateglinide and exogenous glucagon-like peptide-1 in type 2 diabetes. DIABETES RESEARCH AND CLINICAL PRACTICE , 91 . E68-E70. [Journal article]
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DOI: 10.1016/j.diabres.2010.11.033
Abstract
We examined the postprandial glucose regulators nateglinide and GLP-1, separately and in combination, in people with type 2 diabetes. Nateglinide inhibited DPP-4 activity, reduced GLP-1 degradation and enhanced its insulinotropic and blood glucose lowering effect. Combining nateglinide and GLP-1 derivatives may effectively control postprandial glycaemia.
| Item Type: | Journal article |
|---|---|
| Faculties and Schools: | Faculty of Life and Health Sciences Faculty of Life and Health Sciences > School of Biomedical Sciences |
| Research Institutes and Groups: | Biomedical Sciences Research Institute Biomedical Sciences Research Institute > Diabetes |
| ID Code: | 21615 |
| Deposited By: | Dr Nigel Irwin |
| Deposited On: | 28 Mar 2012 16:07 |
| Last Modified: | 28 Mar 2012 16:07 |
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