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The effect of patient gait on the material properties of UHMWPEin hip replacements

Biomedical Sciences Research Institute Computer Science Research Institute Environmental Sciences Research Institute Nanotechnology & Advanced Materials Research Institute

Davey, S, Orr, JF, Buchanan, FJ, Nixon, JR and Bennett, D (2005) The effect of patient gait on the material properties of UHMWPEin hip replacements. Biomaterials, 26 . pp. 4993-5001. [Journal article]

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Abstract

The wear of ultra-high molecular weight polyethylene (UHMWPE) acetabular components in total hip replacements (THRs) hasbeen shown to be highly dependent on the direction of shear. Greatly reduced wear rates have been reported for unidirectional,compared to multidirectional, articulation in vitro. This work for the first time enables investigation of a relationship betweenclinical wear conditions, as determined by patient gait path, and the mechanical and structural changes that occur within theUHMWPE acetabular component. Individual patients’ wear paths were determined prior to revision operation from hip jointkinematics measured by clinical gait analysis. The material properties of the acetabular components removed during the revisionoperation were subsequently analysed. A technique using Fourier transform infra- red analysis (FTIR) was developed to quantifythe orientation of the individual UHMWPE lamellae. This study shows that there is a direct relationship between a patient’s clinicalgait path and the molecular properties of their UHMWPE acetabular socket. Patient kinematics are an important factor affectingthe wear and long-term biocompatibility of UHMWPE used as a bearing surface in THR.r 2005 Elsevier Ltd. All rights reserved.

Item Type:Journal article
Faculties and Schools:Faculty of Computing & Engineering
Faculty of Computing & Engineering > School of Engineering
Research Institutes and Groups:Engineering Research Institute > Nanotechnology & Integrated BioEngineering Centre (NIBEC)
ID Code:21585
Deposited By:Dr Shirley Davey
Deposited On:26 Mar 2012 11:48
Last Modified:26 Mar 2012 11:48

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