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The relationship between short-wavelength-sensitive acuity and macular pigment optical density in the ageing eye.

Biomedical Sciences Research Institute Computer Science Research Institute Environmental Sciences Research Institute Nanotechnology & Advanced Materials Research Institute

Beirne, Raymond (2011) The relationship between short-wavelength-sensitive acuity and macular pigment optical density in the ageing eye. [Other]

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Abstract

Introduction: This study investigates the relationship between foveal short-wavelength-sensitive (SWS) orientation identification acuity and measures of macular pigment optical density (MPOD) in the ageing eye.Methods: Orientation identification acuity was measured in the fovea and at 12 degrees eccentricity (nasal visual field) under S-cone isolating conditions in 62 participants (aged 20 – 71) free from ocular disease and with clear ocular media. MPOD was measured at 0.5 degrees eccentricity from the foveal centre using a heterochromatic flicker photometry based densitometer instrument from MacularMetrics. Results: Reduced SWS orientation identification acuity was associated with increasing age in the fovea (r= -0.57, p<0.01) and at 12 degrees eccentricity (r= -0.28, p=0.03). MPOD was not significantly related to age (r= 0.17, p= 0.18), with mean MPOD for the group being 0.43 (±0.19). There was a significant relationship between the fovea to periphery acuity ratio and increasing age in individuals with lower levels of MPOD (<0.4 log units, 31 participants) (r= -0.46, p= 0.01). There was no significant relationship between the fovea to periphery acuity ratio and increasing age in individuals with higher levels of MPOD (>0.4 log units, 31 participants) (r= -0.17, p= 0.35).Conclusions: MPOD was not significantly related to age in this study. SWS orientation identification acuity declined faster in the fovea than the retinal periphery for the group as a whole. Individuals with lower baseline levels of MPOD (<0.4 log units) may have increased risk of preferential loss of foveal SWS acuity relative to the retinal periphery with increasing age. Further research on the role of macular pigment in preventing or slowing subtle loss of central visual function in the ageing eye is required.

Item Type:Other
Faculties and Schools:Faculty of Life and Health Sciences
Faculty of Life and Health Sciences > School of Biomedical Sciences
Research Institutes and Groups:Biomedical Sciences Research Institute
Biomedical Sciences Research Institute > Vision
ID Code:21178
Deposited By:Dr Raymond Beirne
Deposited On:28 Mar 2012 16:04
Last Modified:28 Mar 2012 16:04

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