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Comparing mfERGs with Estimates of Cone Density from in vivo Imaging of the Photoreceptor Mosaic using a Modified Heidelberg Retina Tomograph.

Biomedical Sciences Research Institute Computer Science Research Institute Environmental Sciences Research Institute Nanotechnology & Advanced Materials Research Institute

Wolsley, Clive, Saunders, Kathryn, Silvestri, Guiliani and Anderson, Roger (2010) Comparing mfERGs with Estimates of Cone Density from in vivo Imaging of the Photoreceptor Mosaic using a Modified Heidelberg Retina Tomograph. Vision Research, 50 (15). pp. 1462-1468. [Journal article]

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DOI: 10.1016/j.visres.2010.04.015

Abstract

The spatial variation in central retinal function determined from mfERG was compared to co-localised measurements of cone density in two normal subjects. Individual cone cells in the parafoveal region of the retina were identified from 1 degrees x1 degrees images of the photoreceptor mosaic using a modified Heidelberg retina tomograph (HRT). The variation in cone density compared well with previous histology and retinal imaging studies and was strongly linearly correlated (r=0.98, p<0.001) with mfERG amplitude within the central retina. Retinal function determined from mfERG amplitude appears to directly reflect the density of the cone cells in this region.

Item Type:Journal article
Faculties and Schools:Faculty of Life and Health Sciences
Faculty of Life and Health Sciences > School of Biomedical Sciences
Research Institutes and Groups:Biomedical Sciences Research Institute
Biomedical Sciences Research Institute > Vision
ID Code:20720
Deposited By:Professor Roger Anderson
Deposited On:10 Jan 2012 14:51
Last Modified:07 Apr 2014 11:52

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