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Associations between whole-blood serotonin and subjective mood in healthy male volunteers

Biomedical Sciences Research Institute Computer Science Research Institute Environmental Sciences Research Institute Nanotechnology & Advanced Materials Research Institute

Williams, E, Stewart-Knox, B, Helander, A, McConville, Christopher, Bradbury, I and Rowland, I (2006) Associations between whole-blood serotonin and subjective mood in healthy male volunteers. BIOLOGICAL PSYCHOLOGY, 71 (2). pp. 171-174. [Journal article]

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DOI: 10.1016/j.biopsycho.2005.03.002

Abstract

Little is known regarding the relationship between how mood is experienced and biochemical factors. This research has explored potential relationships between whole-blood serotonin (5-HT) and subjective mood, measured using the Positive and Negative Affect Schedule (PANAS), in healthy males (n = 23). Univariate linear regression analysis indicated that 5-HT levels were positively related to positive affect (P = 0.002) but not negative affect. Whole-blood 5-HT concentrations therefore appear to predict mood in healthy males. More research using larger samples and including females is needed to explore further associations between biomarkers and subjective measures of mood. (c) 2005 Elsevier B.V. All rights reserved.

Item Type:Journal article
Faculties and Schools:Faculty of Life and Health Sciences
Faculty of Life and Health Sciences > School of Biomedical Sciences
Faculty of Life and Health Sciences > School of Psychology
Research Institutes and Groups:Biomedical Sciences Research Institute
Psychology Research Institute
Biomedical Sciences Research Institute > Northern Ireland Centre for Food and Health (NICHE)
Psychology Research Institute > Health and Wellbeing
ID Code:1718
Deposited By:Mrs Fiona Harkin
Deposited On:23 Dec 2009 09:45
Last Modified:16 Dec 2013 15:15

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