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Clinical diagnostics for homocysteine: a rogue amino acid?

Biomedical Sciences Research Institute Computer Science Research Institute Environmental Sciences Research Institute Nanotechnology & Advanced Materials Research Institute

Newton, LAA, Sandhu, K, Livingstone, C, Leslie, R and Davis, J (2010) Clinical diagnostics for homocysteine: a rogue amino acid? EXPERT REVIEW OF MOLECULAR DIAGNOSTICS, 10 (4). pp. 489-500. [Journal article]

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DOI: 10.1586/ERM.10.19

Abstract

Homocysteine has gathered considerable interest in recent years after being implicated in the pathogenesis of various clinical conditions. It has been an elusive target with many conflicting studies casting some confusion over its significance, and much more needs to be done to ascertain its pathophysiological role especially with respect to regimes aimed at lowering its plasma concentration. Central to this is the development of robust analytical strategies for its determination. This review summarizes the clinical relevance of homocysteine as a diagnostic marker of disease and explores and critically assesses the detection methods that have been developed.

Item Type:Journal article
Faculties and Schools:Faculty of Computing & Engineering
Faculty of Computing & Engineering > School of Engineering
Research Institutes and Groups:Engineering Research Institute
Engineering Research Institute > Nanotechnology & Integrated BioEngineering Centre (NIBEC)
ID Code:14299
Deposited By:Professor James Davis
Deposited On:23 Jun 2010 13:39
Last Modified:18 Aug 2011 11:19

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