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FOURIER-ANALYSIS OF VENTRICULAR-FIBRILLATION OF VARIED ETIOLOGY

Biomedical Sciences Research Institute Computer Science Research Institute Environmental Sciences Research Institute Nanotechnology & Advanced Materials Research Institute

Carlisle, EJF, Allen, JD, Kernohan, George, Anderson, JMCC and Adgey, AAJ (1990) FOURIER-ANALYSIS OF VENTRICULAR-FIBRILLATION OF VARIED ETIOLOGY. EUROPEAN HEART JOURNAL, 11 (2). pp. 173-181. [Journal article]

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URL: http://eurheartj.oxfordjournals.org/content/11/2/173.abstract

Abstract

Fast Fourier Transform analysis was used to study ventricular fibrillation induced by several different methods in 43 greyhounds anaesthetized with sodium pentobarbitone. The dominant frequency at the body surface of ventricular fibrillation induced electrically in non-ischaemic hearts was initially 9-9 ±0-7 Hz, remained above 9 Hz for 70 s and then rapidly fell to 5 Hz. The dominant frequency of ventricular fibrillation induced by acute occlusion (initially 12-3 ± 0-2 Hz), or by reperfusion (12-2 + 0-4 Hz) of the anterior descending branch of the left coronary artery, showed a similar time-course. However, ventricular fibrillation induced by administration of potassium (4-8±0-8 Hz) or ouabain (7-1 ± 11 Hz) was significantly slower. Fibrillation recordedfrom the endocardium of the heart initially showed a similar dominant frequency to that recorded at the body surface, but there was no significant fall in frequency over 3-3 mins. There was little difference in the time-course of fibrillation in the non-ischaemic heart recorded directly from the epicardium or from a surface lead. These findings may be of relevance to the poor response to DC countershock after prolonged ventricular fibrillation, hyperkalaemia or cardiac glycosides.

Item Type:Journal article
Faculties and Schools:Faculty of Computing & Engineering
Faculty of Life and Health Sciences
Faculty of Computing & Engineering > School of Engineering
Faculty of Life and Health Sciences > School of Nursing
Research Institutes and Groups:Engineering Research Institute
Institute of Nursing and Health Research
Engineering Research Institute > Nanotechnology & Integrated BioEngineering Centre (NIBEC)
Institute of Nursing and Health Research > Managing Chronic Illness
ID Code:1308
Deposited By:Professor George Kernohan
Deposited On:19 Apr 2010 11:49
Last Modified:23 Jun 2011 14:51

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