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Integrated urate sensors for detecting wound infection

Biomedical Sciences Research Institute Computer Science Research Institute Environmental Sciences Research Institute Nanotechnology & Advanced Materials Research Institute

Sharp, D and Davis, J (2008) Integrated urate sensors for detecting wound infection. ELECTROCHEMISTRY COMMUNICATIONS, 10 (5). pp. 709-713. [Journal article]

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DOI: 10.1016/j.elecom.2008.02.025

Abstract

The applicability of employing a carbon fibre mesh as the sensing element within a "smart bandage" for assessing urate transformations within wound exudates is evaluated and a novel strategy for the detection of bacterial contamination presented. Prototype sensor assemblies have been designed and their response characteristics towards the periodic monitoring of uric acid within whole blood, serum, blister fluid and microbial culture has been evaluated. The rapid and selective metabolism of urate by Pseudomonas aeruginosa, the bacteria responsible for most adventitious wound infections, has been investigated. A preliminary evaluation of the efficacy of utilizing the microbial response to endogenous wound urate as means of detecting the onset of infection is presented.

Item Type:Journal article
Keywords:carbon fibre; smart bandage; urate; bacteria; wound; microbial; Pseudomonas aeruginosa
Faculties and Schools:Faculty of Computing & Engineering
Faculty of Computing & Engineering > School of Engineering
Research Institutes and Groups:Engineering Research Institute
Engineering Research Institute > Nanotechnology & Integrated BioEngineering Centre (NIBEC)
ID Code:11900
Deposited By:Professor James Davis
Deposited On:14 Feb 2010 15:17
Last Modified:07 Apr 2014 14:15

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