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Carbon fibre composites: Integrated electrochemical sensors for wound management

Biomedical Sciences Research Institute Computer Science Research Institute Environmental Sciences Research Institute Nanotechnology & Advanced Materials Research Institute

Sharp, D, Forsythe, S and Davis, J (2008) Carbon fibre composites: Integrated electrochemical sensors for wound management. JOURNAL OF BIOCHEMISTRY, 144 (1). pp. 87-93. [Journal article]

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DOI: 10.1093/jb/mvn045

Abstract

The applicability of employing a carbon fibre mesh as an electrochemical sensing substructure for assessing urate transformations within wound exudates is evaluated. Prototype sensor assemblies have been designed and their response characteristics towards uric acid and other common physiological components are detailed. Modification of the carbon fibre sensor through surface anodization and the application of cellulose acetate permselective barriers have been shown to lead to optimized responses and much greater sensitivity (1440% increase) and specificity. These could enable the accurate periodic monitoring of uric acid in wound fluid. The performance characteristics of the composite sensors in whole blood, serum and blister fluid have been investigated.

Item Type:Journal article
Keywords:carbon fibre; smart bandage; urate; uric acid; wound infection
Faculties and Schools:Faculty of Computing & Engineering
Faculty of Computing & Engineering > School of Engineering
Research Institutes and Groups:Engineering Research Institute
Engineering Research Institute > Nanotechnology & Integrated BioEngineering Centre (NIBEC)
ID Code:11898
Deposited By:Professor James Davis
Deposited On:14 Feb 2010 15:16
Last Modified:18 Aug 2011 11:18

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