Price, Ruth K., WELCH, RW, Lee-Manion, Alison M., Bradbury, Ian and Strain, JJ (2008) Total phenolics and antioxidant potential in plasma and urine of humans after consumption of wheat bran. CEREAL CHEMISTRY, 85 (2). pp. 152-157. [Journal article]
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The protective effects of whole grain cereals against heart disease and certain cancers may be due, at least partly, to the antioxidant effects of phenolics concentrated in the bran. However, it is unclear to what extent these phenolics are absorbed, and whether these phenolics exert significant physiological antioxidant effects. Thus, this study aimed to compare total phenolics (TP) and antioxidant potential (AOP) in the plasma and urine of humans following consumption of a single meal of unprocessed wheat bran or a refined cereal (ground white rice). Using a randomized cross-over design. 17 adults consumed approximate to 93 g of wheat bran or ground rice after an overnight fast. Baseline and postmeal plasma and urine samples were analyzed for TP (Folin-Ciocalteu method) and AOP (FRAP method). Compared with ground rice, wheat bran gave significantly (P < 0.05) higher plasma TP at 1 hr, and significantly (P < 0.001) higher plasma AOP from 0.5 to 3 hr. Furthermore, compared with ground rice, wheat bran led to consistently higher TP and AOP in urine, and these differences were significant (P < 0.05) at 2 hr. Comparisons with data from a range of other phenolic-rich foods indicated that wheat bran phenolics are relatively well absorbed and may enhance antioxidant status.
|Item Type:||Journal article|
|Faculties and Schools:||Faculty of Life and Health Sciences|
Faculty of Life and Health Sciences > School of Biomedical Sciences
|Research Institutes and Groups:||Biomedical Sciences Research Institute|
Biomedical Sciences Research Institute > Northern Ireland Centre for Food and Health (NICHE)
|Deposited By:||Prof Robert W Welch|
|Deposited On:||05 Feb 2010 09:33|
|Last Modified:||02 Feb 2012 11:30|
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