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A study of the analytical behaviour of selected synthetic and naturally occurring coumarins using liquid chromatography, ion trap mass spectrometry, gas chromatography and polarography and the construction of an appropriate database for coumarin characterisation

Biomedical Sciences Research Institute Computer Science Research Institute Environmental Sciences Research Institute Nanotechnology & Advanced Materials Research Institute

Smyth, Franklin, Ramachandran, VN, Hack, Catherine, Joyce, C and O'Kane, E (2006) A study of the analytical behaviour of selected synthetic and naturally occurring coumarins using liquid chromatography, ion trap mass spectrometry, gas chromatography and polarography and the construction of an appropriate database for coumarin characterisation. ANALYTICA CHIMICA ACTA, 564 (2). pp. 201-210. [Journal article]

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DOI: 10.1016/j.aca.2006.01.102

Abstract

The aim of this paper is to provide analytical chemical information on a range of naturally occurring and synthetic coumarins. This analytical chemical information on liquid chromatography-electrospray ionisation-mass spectrometry (HPLC-ESI-MS), ion trap mass spectrometry (ESI-MS''), gas chromatography-flame ionisation detection (GLC-FID) and polarographic behaviour is then incorporated into a database which is of use in identifying unknown coumarins isolated from natural sources. This paper is also concerned with understanding the effect of functional groups in coumarins on their analytical chemical behaviour using the above techniques. (c) 2006 Elsevier B.V. All rights reserved.

Item Type:Journal article
Faculties and Schools:Faculty of Life and Health Sciences
Faculty of Life and Health Sciences > School of Biomedical Sciences
Research Institutes and Groups:Biomedical Sciences Research Institute
Biomedical Sciences Research Institute > Pharmaceutical Science and Practice
ID Code:1085
Deposited By:Prof W.Franklin Smyth
Deposited On:11 Jan 2010 16:38
Last Modified:04 Aug 2011 09:43

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